BDBM50144322 6-Amino-2-(1H-imidazol-4-yl)-5-methyl-hexanoic acid::CHEMBL69955

SMILES: CC(CN)CCC(C(O)=O)c1cnc[nH]1

InChI Key: InChIKey=GNCKWAGRDBWVQA-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50144322   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Thrombin-activatable fibrinolysis (TAFI) (Homo sapiens (Human))	BDBM50144322 (6-Amino-2-(1H-imidazol-4-yl)-5-methyl-hexanoic aci...) Show SMILES CC(CN)CCC(C(O)=O)c1cnc[nH]1 Show InChI InChI=1S/C10H17N3O2/c1-7(4-11)2-3-8(10(14)15)9-5-12-6-13-9/h5-8H,2-4,11H2,1H3,(H,12,13)(H,14,15)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of human carboxypeptidase B (CPB)				Bioorg Med Chem Lett 14: 2141-5 (2004) Article DOI: 10.1016/j.bmcl.2004.02.033 BindingDB Entry DOI: 10.7270/Q2N8797S
					More data for this Ligand-Target Pair
Carboxypeptidase B2 isoform A (Homo sapiens (Human))	BDBM50144322 (6-Amino-2-(1H-imidazol-4-yl)-5-methyl-hexanoic aci...) Show SMILES CC(CN)CCC(C(O)=O)c1cnc[nH]1 Show InChI InChI=1S/C10H17N3O2/c1-7(4-11)2-3-8(10(14)15)9-5-12-6-13-9/h5-8H,2-4,11H2,1H3,(H,12,13)(H,14,15)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	270	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibitory potency against human TAFIa (thrombin-activatable fibrinolysis inhibitor)				Bioorg Med Chem Lett 14: 2141-5 (2004) Article DOI: 10.1016/j.bmcl.2004.02.033 BindingDB Entry DOI: 10.7270/Q2N8797S
					More data for this Ligand-Target Pair