BDBM50144572 CHEMBL3759635
SMILES: OC(=O)c1cc2CCc3c(cccc3-c2s1)C#N
InChI Key: InChIKey=BDLWMEDOSVLQIN-UHFFFAOYSA-N
Data: 2 EC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Palmitoleoyl-protein carboxylesterase NOTUM (Homo sapiens (Human)) | BDBM50144572 (CHEMBL3759635) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | n/a | n/a | 82 | n/a | n/a | n/a | n/a |
Lexicon Pharmaceuticals Curated by ChEMBL | Assay Description Inhibition of human notum pectinacetylesterase expressed in 293F cells by TCF/LEF CellSensor assay | Bioorg Med Chem Lett 26: 1184-7 (2016) BindingDB Entry DOI: 10.7270/Q2QV3PBN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Palmitoleoyl-protein carboxylesterase NOTUM (Mus musculus) | BDBM50144572 (CHEMBL3759635) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | n/a | n/a | 67 | n/a | n/a | n/a | n/a |
Lexicon Pharmaceuticals Curated by ChEMBL | Assay Description Inhibition of mouse notum pectinacetylesterase expressed in 293F cells by TCF/LEF CellSensor assay | Bioorg Med Chem Lett 26: 1184-7 (2016) BindingDB Entry DOI: 10.7270/Q2QV3PBN | |||||||||||
More data for this Ligand-Target Pair |