BDBM50144711 1-{4-[2-Amino-6-(5-bromo-2-ethoxy-phenyl)-pyrimidin-4-ylamino]-phenyl}-ethanone oxime::CHEMBL72992

SMILES: CCOc1ccc(Br)cc1-c1cc(Nc2ccc(cc2)C(C)N=O)nc(N)n1

InChI Key: InChIKey=CYMKLFUHVUGERW-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50144711   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
1-acylglycerol-3-phosphate O-acyltransferase beta (Homo sapiens (Human))	BDBM50144711 (1-{4-[2-Amino-6-(5-bromo-2-ethoxy-phenyl)-pyrimidi...) Show SMILES CCOc1ccc(Br)cc1-c1cc(Nc2ccc(cc2)C(C)N=O)nc(N)n1 Show InChI InChI=1S/C20H20BrN5O2/c1-3-28-18-9-6-14(21)10-16(18)17-11-19(25-20(22)24-17)23-15-7-4-13(5-8-15)12(2)26-27/h4-12H,3H2,1-2H3,(H3,22,23,24,25)	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	84	n/a	n/a	n/a	n/a	n/a	n/a
Cell Therapeutics, Inc Curated by ChEMBL					Assay Description Inhibitory activity against Lysophosphatidic acid acyltransferase-beta expressed in Sf9 insect cell membranes				Bioorg Med Chem Lett 14: 2303-8 (2004) Article DOI: 10.1016/j.bmcl.2004.01.104 BindingDB Entry DOI: 10.7270/Q2Q23ZPH
					More data for this Ligand-Target Pair