BDBM50144725 CHEMBL424605::N*4*-(4-Bromo-phenyl)-6-(5-chloro-2-methoxy-phenyl)-pyrimidine-2,4-diamine

SMILES: COc1ccc(Cl)cc1-c1cc(Nc2ccc(Br)cc2)nc(N)n1

InChI Key: InChIKey=BCMCLJBSGAKTRO-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50144725   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
1-acylglycerol-3-phosphate O-acyltransferase beta (Homo sapiens (Human))	BDBM50144725 (CHEMBL424605 | N*4*-(4-Bromo-phenyl)-6-(5-chloro-2...) Show SMILES COc1ccc(Cl)cc1-c1cc(Nc2ccc(Br)cc2)nc(N)n1 Show InChI InChI=1S/C17H14BrClN4O/c1-24-15-7-4-11(19)8-13(15)14-9-16(23-17(20)22-14)21-12-5-2-10(18)3-6-12/h2-9H,1H3,(H3,20,21,22,23)	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	28	n/a	n/a	n/a	n/a	n/a	n/a
Cell Therapeutics, Inc Curated by ChEMBL					Assay Description Inhibitory activity against Lysophosphatidic acid acyltransferase-beta expressed in Sf9 insect cell membranes				Bioorg Med Chem Lett 14: 2303-8 (2004) Article DOI: 10.1016/j.bmcl.2004.01.104 BindingDB Entry DOI: 10.7270/Q2Q23ZPH
					More data for this Ligand-Target Pair