BDBM50144730 6-(5-Chloro-2-ethoxy-phenyl)-N*4*-(4-nitro-phenyl)-pyrimidine-2,4-diamine::CHEMBL75167

SMILES: CCOc1ccc(Cl)cc1-c1cc(Nc2ccc(cc2)[N+]([O-])=O)nc(N)n1

InChI Key: InChIKey=DWHPDYVWWJDUIC-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50144730   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
1-acylglycerol-3-phosphate O-acyltransferase beta (Homo sapiens (Human))	BDBM50144730 (6-(5-Chloro-2-ethoxy-phenyl)-N*4*-(4-nitro-phenyl)...) Show SMILES CCOc1ccc(Cl)cc1-c1cc(Nc2ccc(cc2)[N+]([O-])=O)nc(N)n1 Show InChI InChI=1S/C18H16ClN5O3/c1-2-27-16-8-3-11(19)9-14(16)15-10-17(23-18(20)22-15)21-12-4-6-13(7-5-12)24(25)26/h3-10H,2H2,1H3,(H3,20,21,22,23)	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Cell Therapeutics, Inc Curated by ChEMBL					Assay Description Inhibitory activity against Lysophosphatidic acid acyltransferase-beta expressed in Sf9 insect cell membranes				Bioorg Med Chem Lett 14: 2303-8 (2004) Article DOI: 10.1016/j.bmcl.2004.01.104 BindingDB Entry DOI: 10.7270/Q2Q23ZPH
					More data for this Ligand-Target Pair