BDBM50144939 (2R,3R,4R,5R)-2-(2-amino-9H-purin-9-yl)-5-(hydroxymethyl)-3-methyloxolane-3,4-diol::CHEMBL306299

SMILES: C[C@@]1(O)[C@H](O)[C@@H](CO)O[C@H]1n1cnc2cnc(N)nc12

InChI Key: InChIKey=VULPIDXRASQDGN-LUQPRHOASA-N

Data: 1 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50144939   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatitis C virus NS5B RNA-dependent RNA polymerase (Hepatitis C virus)	BDBM50144939 ((2R,3R,4R,5R)-2-(2-amino-9H-purin-9-yl)-5-(hydroxy...) Show SMILES C[C@@]1(O)[C@H](O)[C@@H](CO)O[C@H]1n1cnc2cnc(N)nc12 Show InChI InChI=1S/C11H15N5O4/c1-11(19)7(18)6(3-17)20-9(11)16-4-14-5-2-13-10(12)15-8(5)16/h2,4,6-7,9,17-19H,3H2,1H3,(H2,12,13,15)/t6-,7-,9-,11-/m1/s1	UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a
Isis Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition HCV RNA replication				J Med Chem 47: 2283-95 (2004) Article DOI: 10.1021/jm030424e BindingDB Entry DOI: 10.7270/Q2QZ2BQ3
					More data for this Ligand-Target Pair
Hepatitis C virus NS5B RNA-dependent RNA polymerase (Hepatitis C virus)	BDBM50144939 ((2R,3R,4R,5R)-2-(2-amino-9H-purin-9-yl)-5-(hydroxy...) Show SMILES C[C@@]1(O)[C@H](O)[C@@H](CO)O[C@H]1n1cnc2cnc(N)nc12 Show InChI InChI=1S/C11H15N5O4/c1-11(19)7(18)6(3-17)20-9(11)16-4-14-5-2-13-10(12)15-8(5)16/h2,4,6-7,9,17-19H,3H2,1H3,(H2,12,13,15)/t6-,7-,9-,11-/m1/s1	UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
Isis Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition HCV NS5B-mediated RNA synthesis				J Med Chem 47: 2283-95 (2004) Article DOI: 10.1021/jm030424e BindingDB Entry DOI: 10.7270/Q2QZ2BQ3
					More data for this Ligand-Target Pair