BDBM50144944 CHEMBL3764919

SMILES: CC(C)C[C@H](NC(=O)Nc1c(C)cccc1C)C(=O)NO

InChI Key: InChIKey=JUDSHLVIXVXGCS-LBPRGKRZSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50144944   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Aminopeptidase N (Sus scrofa (Pig))	BDBM50144944 (CHEMBL3764919) Show SMILES CC(C)C[C@H](NC(=O)Nc1c(C)cccc1C)C(=O)NO |r| Show InChI InChI=1S/C15H23N3O3/c1-9(2)8-12(14(19)18-21)16-15(20)17-13-10(3)6-5-7-11(13)4/h5-7,9,12,21H,8H2,1-4H3,(H,18,19)(H2,16,17,20)/t12-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Fudan University Curated by ChEMBL					Assay Description Inhibition of APN in porcine kidney microsomes preincubated for 5 mins before L-leu-p-nitroanilide substrate addition for 30 mins by plate reader ana...				Eur J Med Chem 108: 21-7 (2016) BindingDB Entry DOI: 10.7270/Q2ZC84RN
					More data for this Ligand-Target Pair
Histone deacetylase (HDAC1 and HDAC2) (Homo sapiens (Human))	BDBM50144944 (CHEMBL3764919) Show SMILES CC(C)C[C@H](NC(=O)Nc1c(C)cccc1C)C(=O)NO |r| Show InChI InChI=1S/C15H23N3O3/c1-9(2)8-12(14(19)18-21)16-15(20)17-13-10(3)6-5-7-11(13)4/h5-7,9,12,21H,8H2,1-4H3,(H,18,19)(H2,16,17,20)/t12-/m0/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Fudan University Curated by ChEMBL					Assay Description Inhibition of HDAC1/HDAC2 in human HeLa cells nuclear extract preincubated for 5 mins before Boc-Lys (acetyl)-AMC substrate addition for 30 mins by m...				Eur J Med Chem 108: 21-7 (2016) BindingDB Entry DOI: 10.7270/Q2ZC84RN
					More data for this Ligand-Target Pair
Aminopeptidase N (Homo sapiens (Human))	BDBM50144944 (CHEMBL3764919) Show SMILES CC(C)C[C@H](NC(=O)Nc1c(C)cccc1C)C(=O)NO |r| Show InChI InChI=1S/C15H23N3O3/c1-9(2)8-12(14(19)18-21)16-15(20)17-13-10(3)6-5-7-11(13)4/h5-7,9,12,21H,8H2,1-4H3,(H,18,19)(H2,16,17,20)/t12-/m0/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
Fudan University Curated by ChEMBL					Assay Description Inhibition of APN in human ES2 cells preincubated for 5 mins before L-leu-p-nitroanilide substrate addition for 1 hr by photometry				Eur J Med Chem 108: 21-7 (2016) BindingDB Entry DOI: 10.7270/Q2ZC84RN
					More data for this Ligand-Target Pair