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BDBM50144984 CHEMBL3764259

SMILES: COc1cc2ncnc(Nc3ccc(cc3)-c3ccccn3)c2cc1OC

InChI Key: InChIKey=PGMZHLRDRCCROG-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50144984   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Serine-protein kinase ATM


(Homo sapiens (Human))		BDBM50144984
PNG
(CHEMBL3764259)
Show SMILES COc1cc2ncnc(Nc3ccc(cc3)-c3ccccn3)c2cc1OC
Show InChI InChI=1S/C21H18N4O2/c1-26-19-11-16-18(12-20(19)27-2)23-13-24-21(16)25-15-8-6-14(7-9-15)17-5-3-4-10-22-17/h3-13H,1-2H3,(H,23,24,25)
PDB

UniProtKB/SwissProt
UniProtKB/TrEMBL

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
PubMed
n/an/a 1.25E+4n/an/an/an/an/an/a



Duke University School of Medicine

Curated by ChEMBL


Assay Description
Inhibition of ATM kinase in human MCF7 cells after 1 hr by immunofluorescence assay

J Med Chem 59: 559-77 (2016)


BindingDB Entry DOI: 10.7270/Q2TM7D0W
More data for this
Ligand-Target Pair