BDBM50144997 CHEMBL3764300
SMILES: COCCOc1cc2ncnc(-n3nc(nc3N)-c3ccccn3)c2cc1OCCOC
InChI Key: InChIKey=PBIMPTFJHKSFEY-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Serine-protein kinase ATM (Homo sapiens (Human)) | BDBM50144997 (CHEMBL3764300) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 2.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Duke University School of Medicine Curated by ChEMBL | Assay Description Inhibition of ATM kinase in human MCF7 cells after 1 hr by immunofluorescence assay | J Med Chem 59: 559-77 (2016) BindingDB Entry DOI: 10.7270/Q2TM7D0W | |||||||||||
More data for this Ligand-Target Pair |