null

SMILES: Clc1ccccc1N1CCN(Cc2nc3ncccc3[nH]2)CC1

InChI Key: InChIKey=SVZAUKNERKCTTC-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50145074   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50145074 (2-[4-(2-Chloro-phenyl)-piperazin-1-ylmethyl]-3H-im...) Show SMILES Clc1ccccc1N1CCN(Cc2nc3ncccc3[nH]2)CC1 Show InChI InChI=1S/C17H18ClN5/c18-13-4-1-2-6-15(13)23-10-8-22(9-11-23)12-16-20-14-5-3-7-19-17(14)21-16/h1-7H,8-12H2,(H,19,20,21)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	719	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding affinity against human Dopamine receptor D4 by [3H]-spiperone displacement.				J Med Chem 47: 2348-55 (2004) Article DOI: 10.1021/jm0305669 BindingDB Entry DOI: 10.7270/Q2M61M03
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50145074 (2-[4-(2-Chloro-phenyl)-piperazin-1-ylmethyl]-3H-im...) Show SMILES Clc1ccccc1N1CCN(Cc2nc3ncccc3[nH]2)CC1 Show InChI InChI=1S/C17H18ClN5/c18-13-4-1-2-6-15(13)23-10-8-22(9-11-23)12-16-20-14-5-3-7-19-17(14)21-16/h1-7H,8-12H2,(H,19,20,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding affinity against human Dopamine receptor D2 using [3H]spiperone as radioligand				J Med Chem 47: 2348-55 (2004) Article DOI: 10.1021/jm0305669 BindingDB Entry DOI: 10.7270/Q2M61M03
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50145074 (2-[4-(2-Chloro-phenyl)-piperazin-1-ylmethyl]-3H-im...) Show SMILES Clc1ccccc1N1CCN(Cc2nc3ncccc3[nH]2)CC1 Show InChI InChI=1S/C17H18ClN5/c18-13-4-1-2-6-15(13)23-10-8-22(9-11-23)12-16-20-14-5-3-7-19-17(14)21-16/h1-7H,8-12H2,(H,19,20,21)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Effective concentration against human Dopamine receptor D4				J Med Chem 47: 2348-55 (2004) Article DOI: 10.1021/jm0305669 BindingDB Entry DOI: 10.7270/Q2M61M03
					More data for this Ligand-Target Pair