BDBM50145272 2-(Cyclopropylmethyl-methyl-amino)-1-{4-[(9-fluoro-5,6-dihydro-4H-3-thia-1-aza-benzo[e]azulen-2-ylamino)-methyl]-piperidin-1-yl}-ethanone::CHEMBL310670

SMILES: CN(CC1CC1)CC(=O)N1CCC(CNc2nc-3c(CCCc4ccc(F)cc-34)s2)CC1

InChI Key: InChIKey=HGOZULLDWRICPZ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50145272   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuropeptide Y receptor type 5 ( NPY Y5) (Homo sapiens (Human))	BDBM50145272 (2-(Cyclopropylmethyl-methyl-amino)-1-{4-[(9-fluoro...) Show SMILES CN(CC1CC1)CC(=O)N1CCC(CNc2nc-3c(CCCc4ccc(F)cc-34)s2)CC1 Show InChI InChI=1S/C25H33FN4OS/c1-29(15-18-5-6-18)16-23(31)30-11-9-17(10-12-30)14-27-25-28-24-21-13-20(26)8-7-19(21)3-2-4-22(24)32-25/h7-8,13,17-18H,2-6,9-12,14-16H2,1H3,(H,27,28)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Pharma AG Curated by ChEMBL					Assay Description In vitro binding affinity of the compound against human neuropeptide Y5 receptor				Bioorg Med Chem Lett 14: 2451-7 (2004) Article DOI: 10.1016/j.bmcl.2004.03.014 BindingDB Entry DOI: 10.7270/Q2WM1CV1
					More data for this Ligand-Target Pair