BDBM50145282 1-{4-[(9-Fluoro-5,6-dihydro-4H-3-thia-1-aza-benzo[e]azulen-2-ylamino)-methyl]-piperidin-1-yl}-2-methyl-propan-1-one::CHEMBL81484

SMILES: CC(C)C(=O)N1CCC(CNc2nc-3c(CCCc4ccc(F)cc-34)s2)CC1

InChI Key: InChIKey=KKMVXAAPKLBRBH-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50145282   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuropeptide Y receptor type 5 ( NPY Y5) (Homo sapiens (Human))	BDBM50145282 (1-{4-[(9-Fluoro-5,6-dihydro-4H-3-thia-1-aza-benzo[...) Show SMILES CC(C)C(=O)N1CCC(CNc2nc-3c(CCCc4ccc(F)cc-34)s2)CC1 Show InChI InChI=1S/C22H28FN3OS/c1-14(2)21(27)26-10-8-15(9-11-26)13-24-22-25-20-18-12-17(23)7-6-16(18)4-3-5-19(20)28-22/h6-7,12,14-15H,3-5,8-11,13H2,1-2H3,(H,24,25)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Pharma AG Curated by ChEMBL					Assay Description In vitro binding affinity of the compound against human neuropeptide Y5 receptor				Bioorg Med Chem Lett 14: 2451-7 (2004) Article DOI: 10.1016/j.bmcl.2004.03.014 BindingDB Entry DOI: 10.7270/Q2WM1CV1
					More data for this Ligand-Target Pair