BDBM50145384 CHEMBL3764205
SMILES: COC(=O)c1c(NC2CCCCC2)c(=O)c(O)c2oc3cc(ccc3nc12)N(C)C
InChI Key: InChIKey=ZOLGOJCVVCOTKC-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Low-density lipoprotein receptor-related protein 6 (Homo sapiens (Human)) | BDBM50145384 (CHEMBL3764205) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 4.06E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Aristotle University of Thessaloniki Curated by ChEMBL | Assay Description Binding affinity to human LRP6 expressed in HEK293 cells assessed as inhibition of DKK1/LRP6 interaction using compound pre-treated DKK1 conditioned ... | Bioorg Med Chem 24: 1014-22 (2016) BindingDB Entry DOI: 10.7270/Q2J67JRS | |||||||||||
More data for this Ligand-Target Pair |