BDBM50145590 CHEMBL3764761

SMILES: Cl.Clc1ccc(cc1)C(N1CCN(CCNC(=O)c2ccncc2)CC1)c1ccccc1

InChI Key: InChIKey=USVZGTQLVOQHII-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50145590   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50145590 (CHEMBL3764761) Show SMILES Cl.Clc1ccc(cc1)C(N1CCN(CCNC(=O)c2ccncc2)CC1)c1ccccc1 Show InChI InChI=1S/C25H27ClN4O.ClH/c26-23-8-6-21(7-9-23)24(20-4-2-1-3-5-20)30-18-16-29(17-19-30)15-14-28-25(31)22-10-12-27-13-11-22;/h1-13,24H,14-19H2,(H,28,31);1H	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.658	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Dipartimento di Farmacia Universit£ di Napoli"Federico II" Curated by ChEMBL					Assay Description Displacement of [3H]8-OH-DPAT from 5HT1A receptor in Sprague-Dawley rat brain cortex incubated for 30 mins by liquid scintillation counting analysis				Eur J Med Chem 110: 133-50 (2016) BindingDB Entry DOI: 10.7270/Q24X59N9
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50145590 (CHEMBL3764761) Show SMILES Cl.Clc1ccc(cc1)C(N1CCN(CCNC(=O)c2ccncc2)CC1)c1ccccc1 Show InChI InChI=1S/C25H27ClN4O.ClH/c26-23-8-6-21(7-9-23)24(20-4-2-1-3-5-20)30-18-16-29(17-19-30)15-14-28-25(31)22-10-12-27-13-11-22;/h1-13,24H,14-19H2,(H,28,31);1H	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	6.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Dipartimento di Farmacia Universit£ di Napoli"Federico II" Curated by ChEMBL					Assay Description Displacement of [3H]ketanserin from 5HT2A receptor in Sprague-Dawley rat brain cortex incubated for 15 mins by liquid scintillation counting analysis				Eur J Med Chem 110: 133-50 (2016) BindingDB Entry DOI: 10.7270/Q24X59N9
					More data for this Ligand-Target Pair
Serotonin (5-HT) receptor (Rattus norvegicus (Rat))	BDBM50145590 (CHEMBL3764761) Show SMILES Cl.Clc1ccc(cc1)C(N1CCN(CCNC(=O)c2ccncc2)CC1)c1ccccc1 Show InChI InChI=1S/C25H27ClN4O.ClH/c26-23-8-6-21(7-9-23)24(20-4-2-1-3-5-20)30-18-16-29(17-19-30)15-14-28-25(31)22-10-12-27-13-11-22;/h1-13,24H,14-19H2,(H,28,31);1H	KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	55	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Dipartimento di Farmacia Universit£ di Napoli"Federico II" Curated by ChEMBL					Assay Description Displacement of [3H]mesulergine from 5HT2C receptor in Sprague-Dawley rat brain cortex incubated for 15 mins by liquid scintillation counting analysi...				Eur J Med Chem 110: 133-50 (2016) BindingDB Entry DOI: 10.7270/Q24X59N9
					More data for this Ligand-Target Pair