BDBM50145714 3-{4-[2-(2-Biphenyl-4-yl-5-methyl-oxazol-4-yl)-ethoxy]-phenyl}-2-methyl-2-phenoxy-propionic acid::CHEMBL312717

SMILES: Cc1oc(nc1CCOc1ccc(CC(C)(Oc2ccccc2)C(O)=O)cc1)-c1ccc(cc1)-c1ccccc1

InChI Key: InChIKey=BWQAEQBADOVIBT-UHFFFAOYSA-N

Data: 4 IC50  4 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50145714   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Peroxisome proliferator-activated receptor alpha (PPAR alpha) (Homo sapiens (Human))	BDBM50145714 (3-{4-[2-(2-Biphenyl-4-yl-5-methyl-oxazol-4-yl)-eth...) Show SMILES Cc1oc(nc1CCOc1ccc(CC(C)(Oc2ccccc2)C(O)=O)cc1)-c1ccc(cc1)-c1ccccc1 Show InChI InChI=1S/C34H31NO5/c1-24-31(35-32(39-24)28-17-15-27(16-18-28)26-9-5-3-6-10-26)21-22-38-29-19-13-25(14-20-29)23-34(2,33(36)37)40-30-11-7-4-8-12-30/h3-20H,21-23H2,1-2H3,(H,36,37)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	69	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Transcriptional activation of reporter assay by human Peroxisome proliferator activated receptor alpha in CV-1 cells				J Med Chem 47: 2422-5 (2004) Article DOI: 10.1021/jm0342616 BindingDB Entry DOI: 10.7270/Q2TQ6100
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor (Homo sapiens (Human))	BDBM50145714 (3-{4-[2-(2-Biphenyl-4-yl-5-methyl-oxazol-4-yl)-eth...) Show SMILES Cc1oc(nc1CCOc1ccc(CC(C)(Oc2ccccc2)C(O)=O)cc1)-c1ccc(cc1)-c1ccccc1 Show InChI InChI=1S/C34H31NO5/c1-24-31(35-32(39-24)28-17-15-27(16-18-28)26-9-5-3-6-10-26)21-22-38-29-19-13-25(14-20-29)23-34(2,33(36)37)40-30-11-7-4-8-12-30/h3-20H,21-23H2,1-2H3,(H,36,37)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	169	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Displacement of PPARgamma agonist from human PPAR gamma receptor				J Med Chem 47: 2422-5 (2004) Article DOI: 10.1021/jm0342616 BindingDB Entry DOI: 10.7270/Q2TQ6100
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha) (Homo sapiens (Human))	BDBM50145714 (3-{4-[2-(2-Biphenyl-4-yl-5-methyl-oxazol-4-yl)-eth...) Show SMILES Cc1oc(nc1CCOc1ccc(CC(C)(Oc2ccccc2)C(O)=O)cc1)-c1ccc(cc1)-c1ccccc1 Show InChI InChI=1S/C34H31NO5/c1-24-31(35-32(39-24)28-17-15-27(16-18-28)26-9-5-3-6-10-26)21-22-38-29-19-13-25(14-20-29)23-34(2,33(36)37)40-30-11-7-4-8-12-30/h3-20H,21-23H2,1-2H3,(H,36,37)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	503	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Displacement of PPARalpha/delta agonist from human Peroxisome proliferator activated receptor alpha				J Med Chem 47: 2422-5 (2004) Article DOI: 10.1021/jm0342616 BindingDB Entry DOI: 10.7270/Q2TQ6100
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha) (Homo sapiens (Human))	BDBM50145714 (3-{4-[2-(2-Biphenyl-4-yl-5-methyl-oxazol-4-yl)-eth...) Show SMILES Cc1oc(nc1CCOc1ccc(CC(C)(Oc2ccccc2)C(O)=O)cc1)-c1ccc(cc1)-c1ccccc1 Show InChI InChI=1S/C34H31NO5/c1-24-31(35-32(39-24)28-17-15-27(16-18-28)26-9-5-3-6-10-26)21-22-38-29-19-13-25(14-20-29)23-34(2,33(36)37)40-30-11-7-4-8-12-30/h3-20H,21-23H2,1-2H3,(H,36,37)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	503	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description In vitro inhibition of human Peroxisome proliferator activated receptor alpha				Bioorg Med Chem Lett 14: 6113-6 (2004) Article DOI: 10.1016/j.bmcl.2004.09.031 BindingDB Entry DOI: 10.7270/Q2QN67J1
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha) (Homo sapiens (Human))	BDBM50145714 (3-{4-[2-(2-Biphenyl-4-yl-5-methyl-oxazol-4-yl)-eth...) Show SMILES Cc1oc(nc1CCOc1ccc(CC(C)(Oc2ccccc2)C(O)=O)cc1)-c1ccc(cc1)-c1ccccc1 Show InChI InChI=1S/C34H31NO5/c1-24-31(35-32(39-24)28-17-15-27(16-18-28)26-9-5-3-6-10-26)21-22-38-29-19-13-25(14-20-29)23-34(2,33(36)37)40-30-11-7-4-8-12-30/h3-20H,21-23H2,1-2H3,(H,36,37)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	69	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Transactivation activity for human Peroxisome proliferator activated receptor alpha				Bioorg Med Chem Lett 14: 6113-6 (2004) Article DOI: 10.1016/j.bmcl.2004.09.031 BindingDB Entry DOI: 10.7270/Q2QN67J1
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Mus musculus)	BDBM50145714 (3-{4-[2-(2-Biphenyl-4-yl-5-methyl-oxazol-4-yl)-eth...) Show SMILES Cc1oc(nc1CCOc1ccc(CC(C)(Oc2ccccc2)C(O)=O)cc1)-c1ccc(cc1)-c1ccccc1 Show InChI InChI=1S/C34H31NO5/c1-24-31(35-32(39-24)28-17-15-27(16-18-28)26-9-5-3-6-10-26)21-22-38-29-19-13-25(14-20-29)23-34(2,33(36)37)40-30-11-7-4-8-12-30/h3-20H,21-23H2,1-2H3,(H,36,37)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	7.02E+3	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description In vitro inhibition of mouse Peroxisome proliferator activated receptor alpha				Bioorg Med Chem Lett 14: 6113-6 (2004) Article DOI: 10.1016/j.bmcl.2004.09.031 BindingDB Entry DOI: 10.7270/Q2QN67J1
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Mus musculus)	BDBM50145714 (3-{4-[2-(2-Biphenyl-4-yl-5-methyl-oxazol-4-yl)-eth...) Show SMILES Cc1oc(nc1CCOc1ccc(CC(C)(Oc2ccccc2)C(O)=O)cc1)-c1ccc(cc1)-c1ccccc1 Show InChI InChI=1S/C34H31NO5/c1-24-31(35-32(39-24)28-17-15-27(16-18-28)26-9-5-3-6-10-26)21-22-38-29-19-13-25(14-20-29)23-34(2,33(36)37)40-30-11-7-4-8-12-30/h3-20H,21-23H2,1-2H3,(H,36,37)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	2.34E+3	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Transactivation activity for mouse Peroxisome proliferator activated receptor alpha				Bioorg Med Chem Lett 14: 6113-6 (2004) Article DOI: 10.1016/j.bmcl.2004.09.031 BindingDB Entry DOI: 10.7270/Q2QN67J1
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor (Homo sapiens (Human))	BDBM50145714 (3-{4-[2-(2-Biphenyl-4-yl-5-methyl-oxazol-4-yl)-eth...) Show SMILES Cc1oc(nc1CCOc1ccc(CC(C)(Oc2ccccc2)C(O)=O)cc1)-c1ccc(cc1)-c1ccccc1 Show InChI InChI=1S/C34H31NO5/c1-24-31(35-32(39-24)28-17-15-27(16-18-28)26-9-5-3-6-10-26)21-22-38-29-19-13-25(14-20-29)23-34(2,33(36)37)40-30-11-7-4-8-12-30/h3-20H,21-23H2,1-2H3,(H,36,37)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	7	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Transcriptional activation of reporter assay by PPAR gamma receptor in CV-1 cells				J Med Chem 47: 2422-5 (2004) Article DOI: 10.1021/jm0342616 BindingDB Entry DOI: 10.7270/Q2TQ6100
					More data for this Ligand-Target Pair