BDBM50145716 2-{4-[2-(5-Methyl-2-phenyl-oxazol-4-yl)-ethoxy]-benzyl}-2-phenoxy-butyric acid::CHEMBL78529
SMILES: CCC(Cc1ccc(OCCc2nc(oc2C)-c2ccccc2)cc1)(Oc1ccccc1)C(O)=O
InChI Key: InChIKey=PWZALNZYZAMBJL-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Peroxisome proliferator-activated receptor delta (Homo sapiens (Human)) | BDBM50145716 (2-{4-[2-(5-Methyl-2-phenyl-oxazol-4-yl)-ethoxy]-be...) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 5.07E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories Curated by ChEMBL | Assay Description Displacement of PPARalpha/delta agonist from human Peroxisome proliferator activated receptor delta | J Med Chem 47: 2422-5 (2004) Article DOI: 10.1021/jm0342616 BindingDB Entry DOI: 10.7270/Q2TQ6100 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Peroxisome proliferator-activated receptor (Homo sapiens (Human)) | BDBM50145716 (2-{4-[2-(5-Methyl-2-phenyl-oxazol-4-yl)-ethoxy]-be...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 285 | n/a | n/a | n/a | n/a |
Lilly Research Laboratories Curated by ChEMBL | Assay Description Transcriptional activation of reporter assay by PPAR gamma receptor in CV-1 cells | J Med Chem 47: 2422-5 (2004) Article DOI: 10.1021/jm0342616 BindingDB Entry DOI: 10.7270/Q2TQ6100 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Peroxisome proliferator-activated receptor (Homo sapiens (Human)) | BDBM50145716 (2-{4-[2-(5-Methyl-2-phenyl-oxazol-4-yl)-ethoxy]-be...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 290 | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories Curated by ChEMBL | Assay Description Displacement of PPARgamma agonist from human PPAR gamma receptor | J Med Chem 47: 2422-5 (2004) Article DOI: 10.1021/jm0342616 BindingDB Entry DOI: 10.7270/Q2TQ6100 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Peroxisome proliferator-activated receptor alpha (PPAR alpha) (Homo sapiens (Human)) | BDBM50145716 (2-{4-[2-(5-Methyl-2-phenyl-oxazol-4-yl)-ethoxy]-be...) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 75 | n/a | n/a | n/a | n/a |
Lilly Research Laboratories Curated by ChEMBL | Assay Description Transcriptional activation of reporter assay by human Peroxisome proliferator activated receptor alpha in CV-1 cells | J Med Chem 47: 2422-5 (2004) Article DOI: 10.1021/jm0342616 BindingDB Entry DOI: 10.7270/Q2TQ6100 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Peroxisome proliferator-activated receptor alpha (PPAR alpha) (Homo sapiens (Human)) | BDBM50145716 (2-{4-[2-(5-Methyl-2-phenyl-oxazol-4-yl)-ethoxy]-be...) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 473 | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories Curated by ChEMBL | Assay Description Displacement of PPARalpha/delta agonist from human Peroxisome proliferator activated receptor alpha | J Med Chem 47: 2422-5 (2004) Article DOI: 10.1021/jm0342616 BindingDB Entry DOI: 10.7270/Q2TQ6100 | |||||||||||
More data for this Ligand-Target Pair |