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SMILES: Cc1ccc(NC(C(=O)CCc2ccncc2)c2ccccc2Br)c(Cl)c1

InChI Key: InChIKey=XAXSLDGZQYGHOZ-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50145730   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Corticotropin-releasing factor receptor 1


(Homo sapiens (Human))		BDBM50145730
PNG
(1-(2-Bromo-phenyl)-1-(2-chloro-4-methyl-phenylamin...)
Show SMILES Cc1ccc(NC(C(=O)CCc2ccncc2)c2ccccc2Br)c(Cl)c1
Show InChI InChI=1S/C22H20BrClN2O/c1-15-6-8-20(19(24)14-15)26-22(17-4-2-3-5-18(17)23)21(27)9-7-16-10-12-25-13-11-16/h2-6,8,10-14,22,26H,7,9H2,1H3
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Article
PubMed
 1.04E+3n/an/an/an/an/an/an/an/a



Bristol-Myers Squibb Pharma Research Laboratories

Curated by ChEMBL


Assay Description
Binding affinity of compound towards human Corticotropin releasing factor receptor 1

J Med Chem 47: 2426-9 (2004)


Article DOI: 10.1021/jm049974i
BindingDB Entry DOI: 10.7270/Q2PZ5888
More data for this
Ligand-Target Pair