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SMILES: Clc1ccc(NC(C(=O)CCc2ccncc2)c2ccccc2Br)c(Cl)c1

InChI Key: InChIKey=AUGIDTNFOJJKQB-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50145735   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Corticotropin-releasing factor receptor 1


(Homo sapiens (Human))		BDBM50145735
PNG
(1-(2-Bromo-phenyl)-1-(2,4-dichloro-phenylamino)-4-...)
Show SMILES Clc1ccc(NC(C(=O)CCc2ccncc2)c2ccccc2Br)c(Cl)c1
Show InChI InChI=1S/C21H17BrCl2N2O/c22-17-4-2-1-3-16(17)21(26-19-7-6-15(23)13-18(19)24)20(27)8-5-14-9-11-25-12-10-14/h1-4,6-7,9-13,21,26H,5,8H2
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Article
PubMed
 204n/an/an/an/an/an/an/an/a



Bristol-Myers Squibb Pharma Research Laboratories

Curated by ChEMBL


Assay Description
Binding affinity towards human corticotropin releasing factor (h-CRF1) receptor

J Med Chem 47: 2426-9 (2004)


Article DOI: 10.1021/jm049974i
BindingDB Entry DOI: 10.7270/Q2PZ5888
More data for this
Ligand-Target Pair