BindingDB logo
myBDB logout

null

SMILES: COc1ccc(cc1OC)C(=O)C(Nc1ccc(Cl)cc1Cl)c1ccccc1C

InChI Key: InChIKey=CBJPBRZXQFWNOI-UHFFFAOYSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50145747   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Corticotropin-releasing factor receptor 1


(Homo sapiens (Human))		BDBM50145747
PNG
(2-(2,4-Dichloro-phenylamino)-1-(3,4-dimethoxy-phen...)
Show SMILES COc1ccc(cc1OC)C(=O)C(Nc1ccc(Cl)cc1Cl)c1ccccc1C
Show InChI InChI=1S/C23H21Cl2NO3/c1-14-6-4-5-7-17(14)22(26-19-10-9-16(24)13-18(19)25)23(27)15-8-11-20(28-2)21(12-15)29-3/h4-13,22,26H,1-3H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
>1.00E+4n/an/an/an/an/an/an/an/a



Bristol-Myers Squibb Pharma Research Laboratories

Curated by ChEMBL


Assay Description
Binding affinity towards human corticotropin releasing factor (h-CRF1) receptor

J Med Chem 47: 2426-9 (2004)


Article DOI: 10.1021/jm049974i
BindingDB Entry DOI: 10.7270/Q2PZ5888
More data for this
Ligand-Target Pair