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SMILES: Cc1ccc(NC(C(=O)CCc2cnc[nH]2)c2ccccc2Br)c(Cl)c1

InChI Key: InChIKey=CKEWBVKRLQFWPT-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50145748   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Corticotropin-releasing factor receptor 1


(Homo sapiens (Human))		BDBM50145748
PNG
(1-(2-Bromo-phenyl)-1-(2-chloro-4-methyl-phenylamin...)
Show SMILES Cc1ccc(NC(C(=O)CCc2cnc[nH]2)c2ccccc2Br)c(Cl)c1
Show InChI InChI=1S/C20H19BrClN3O/c1-13-6-8-18(17(22)10-13)25-20(15-4-2-3-5-16(15)21)19(26)9-7-14-11-23-12-24-14/h2-6,8,10-12,20,25H,7,9H2,1H3,(H,23,24)
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Article
PubMed
>1.00E+4n/an/an/an/an/an/an/an/a



Bristol-Myers Squibb Pharma Research Laboratories

Curated by ChEMBL


Assay Description
Binding affinity towards human corticotropin releasing factor (h-CRF1) receptor

J Med Chem 47: 2426-9 (2004)


Article DOI: 10.1021/jm049974i
BindingDB Entry DOI: 10.7270/Q2PZ5888
More data for this
Ligand-Target Pair