BDBM50145753 1-(2-Chloro-4-methyl-phenylamino)-1-(3-chloro-phenyl)-4-pyridin-4-yl-butan-2-one::CHEMBL311997

SMILES: Cc1ccc(NC(C(=O)CCc2ccncc2)c2cccc(Cl)c2)c(Cl)c1

InChI Key: InChIKey=KPKKZKQGVFPHIP-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50145753   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50145753 (1-(2-Chloro-4-methyl-phenylamino)-1-(3-chloro-phen...) Show SMILES Cc1ccc(NC(C(=O)CCc2ccncc2)c2cccc(Cl)c2)c(Cl)c1 Show InChI InChI=1S/C22H20Cl2N2O/c1-15-5-7-20(19(24)13-15)26-22(17-3-2-4-18(23)14-17)21(27)8-6-16-9-11-25-12-10-16/h2-5,7,9-14,22,26H,6,8H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharma Research Laboratories Curated by ChEMBL					Assay Description Binding affinity towards human corticotropin releasing factor (h-CRF1) receptor				J Med Chem 47: 2426-9 (2004) Article DOI: 10.1021/jm049974i BindingDB Entry DOI: 10.7270/Q2PZ5888
					More data for this Ligand-Target Pair