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SMILES: Cc1ccc(NC(C(=O)CCc2ccncc2)c2ccccc2C)c(c1)C(F)(F)F

InChI Key: InChIKey=LKQIIIZDHHYDSW-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50145755   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Corticotropin-releasing factor receptor 1


(Homo sapiens (Human))		BDBM50145755
PNG
(1-(4-Methyl-2-trifluoromethyl-phenylamino)-4-pyrid...)
Show SMILES Cc1ccc(NC(C(=O)CCc2ccncc2)c2ccccc2C)c(c1)C(F)(F)F
Show InChI InChI=1S/C24H23F3N2O/c1-16-7-9-21(20(15-16)24(25,26)27)29-23(19-6-4-3-5-17(19)2)22(30)10-8-18-11-13-28-14-12-18/h3-7,9,11-15,23,29H,8,10H2,1-2H3
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Article
PubMed
 641n/an/an/an/an/an/an/an/a



Bristol-Myers Squibb Pharma Research Laboratories

Curated by ChEMBL


Assay Description
Binding affinity towards human corticotropin releasing factor (h-CRF1) receptor

J Med Chem 47: 2426-9 (2004)


Article DOI: 10.1021/jm049974i
BindingDB Entry DOI: 10.7270/Q2PZ5888
More data for this
Ligand-Target Pair