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SMILES: COc1cccc(OC)c1C(Nc1ccc(C)cc1Cl)C(=O)CCc1ccncc1

InChI Key: InChIKey=OHZCUVCSIVLPOA-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50145756   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Corticotropin-releasing factor receptor 1


(Homo sapiens (Human))		BDBM50145756
PNG
(1-(2-Chloro-4-methyl-phenylamino)-1-(2,6-dimethoxy...)
Show SMILES COc1cccc(OC)c1C(Nc1ccc(C)cc1Cl)C(=O)CCc1ccncc1
Show InChI InChI=1S/C24H25ClN2O3/c1-16-7-9-19(18(25)15-16)27-24(20(28)10-8-17-11-13-26-14-12-17)23-21(29-2)5-4-6-22(23)30-3/h4-7,9,11-15,24,27H,8,10H2,1-3H3
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Article
PubMed
>1.00E+4n/an/an/an/an/an/an/an/a



Bristol-Myers Squibb Pharma Research Laboratories

Curated by ChEMBL


Assay Description
Binding affinity towards human corticotropin releasing factor (h-CRF1) receptor

J Med Chem 47: 2426-9 (2004)


Article DOI: 10.1021/jm049974i
BindingDB Entry DOI: 10.7270/Q2PZ5888
More data for this
Ligand-Target Pair