BDBM50145761 (S)-1-(2,4-Dichloro-phenylamino)-4-pyridin-4-yl-1-o-tolyl-butan-2-one::CHEMBL81760

SMILES: Cc1ccccc1[C@H](Nc1ccc(Cl)cc1Cl)C(=O)CCc1ccncc1

InChI Key: InChIKey=HUFVNPMCGTUYCW-QFIPXVFZSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50145761   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50145761 ((S)-1-(2,4-Dichloro-phenylamino)-4-pyridin-4-yl-1-...) Show SMILES Cc1ccccc1[C@H](Nc1ccc(Cl)cc1Cl)C(=O)CCc1ccncc1 Show InChI InChI=1S/C22H20Cl2N2O/c1-15-4-2-3-5-18(15)22(26-20-8-7-17(23)14-19(20)24)21(27)9-6-16-10-12-25-13-11-16/h2-5,7-8,10-14,22,26H,6,9H2,1H3/t22-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.18E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharma Research Laboratories Curated by ChEMBL					Assay Description Binding affinity towards human corticotropin releasing factor (h-CRF1) receptor				J Med Chem 47: 2426-9 (2004) Article DOI: 10.1021/jm049974i BindingDB Entry DOI: 10.7270/Q2PZ5888
					More data for this Ligand-Target Pair