BDBM50145861 CHEMBL3765823

SMILES: Cc1c(N[C@@H]2CCCC[C@@]2(C)O)ccc(C#N)c1Cl

InChI Key: InChIKey=LRQSPCAZHXKTHC-UKRRQHHQSA-N

Data: 4 KI  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50145861   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Androgen receptor (Homo sapiens (Human))	BDBM50145861 (CHEMBL3765823) Show SMILES Cc1c(N[C@@H]2CCCC[C@@]2(C)O)ccc(C#N)c1Cl |r| Show InChI InChI=1S/C15H19ClN2O/c1-10-12(7-6-11(9-17)14(10)16)18-13-5-3-4-8-15(13,2)19/h6-7,13,18-19H,3-5,8H2,1-2H3/t13-,15-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	17	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]-methyltrienolone from androgen receptor (unknown origin) expressed in HEK293 cell lysate incubated overnight by microbeta scinti...				J Med Chem 59: 750-5 (2016) BindingDB Entry DOI: 10.7270/Q2H70HQ9
					More data for this Ligand-Target Pair
Mineralocorticoid receptor (Homo sapiens (Human))	BDBM50145861 (CHEMBL3765823) Show SMILES Cc1c(N[C@@H]2CCCC[C@@]2(C)O)ccc(C#N)c1Cl |r| Show InChI InChI=1S/C15H19ClN2O/c1-10-12(7-6-11(9-17)14(10)16)18-13-5-3-4-8-15(13,2)19/h6-7,13,18-19H,3-5,8H2,1-2H3/t13-,15-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	415	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]-aldosterone from mineralocorticoid receptor (unknown origin) expressed in HEK293 cell lysate incubated overnight by microbeta sc...				J Med Chem 59: 750-5 (2016) BindingDB Entry DOI: 10.7270/Q2H70HQ9
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50145861 (CHEMBL3765823) Show SMILES Cc1c(N[C@@H]2CCCC[C@@]2(C)O)ccc(C#N)c1Cl |r| Show InChI InChI=1S/C15H19ClN2O/c1-10-12(7-6-11(9-17)14(10)16)18-13-5-3-4-8-15(13,2)19/h6-7,13,18-19H,3-5,8H2,1-2H3/t13-,15-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	520	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]-methyltrienolone from progesterone receptor (unknown origin) expressed in HEK293 cell lysate incubated overnight by microbeta sc...				J Med Chem 59: 750-5 (2016) BindingDB Entry DOI: 10.7270/Q2H70HQ9
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50145861 (CHEMBL3765823) Show SMILES Cc1c(N[C@@H]2CCCC[C@@]2(C)O)ccc(C#N)c1Cl |r| Show InChI InChI=1S/C15H19ClN2O/c1-10-12(7-6-11(9-17)14(10)16)18-13-5-3-4-8-15(13,2)19/h6-7,13,18-19H,3-5,8H2,1-2H3/t13-,15-/m1/s1	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	>3.12E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]-dexamethasone from glucocorticoid receptor (unknown origin) expressed in HEK293 cell lysate incubated overnight by microbeta sci...				J Med Chem 59: 750-5 (2016) BindingDB Entry DOI: 10.7270/Q2H70HQ9
					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM50145861 (CHEMBL3765823) Show SMILES Cc1c(N[C@@H]2CCCC[C@@]2(C)O)ccc(C#N)c1Cl |r| Show InChI InChI=1S/C15H19ClN2O/c1-10-12(7-6-11(9-17)14(10)16)18-13-5-3-4-8-15(13,2)19/h6-7,13,18-19H,3-5,8H2,1-2H3/t13-,15-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	4.90	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Agonist activity at human androgen receptor expressed in mouse C2C12 cells cotransfected with GRE/ARE reporter plasmid assessed as receptor transacti...				J Med Chem 59: 750-5 (2016) BindingDB Entry DOI: 10.7270/Q2H70HQ9
					More data for this Ligand-Target Pair