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BDBM50145996 (1R,5S)-3-((S)-2-Amino-3-methyl-pentanoyl)-3-aza-bicyclo[3.1.0]hexane-2-carbonitrile; TFA::CHEMBL327435

SMILES: CCC(C)[C@H](N)C(=O)N1C[C@H]2C[C@H]2C1C#N

InChI Key: InChIKey=YVPZBTSCIXRSNT-ISPFLSOSSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50145996   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Dipeptidyl peptidase IV


(Sus scrofa (pig))
BDBM50145996
PNG
((1R,5S)-3-((S)-2-Amino-3-methyl-pentanoyl)-3-aza-b...)
Show SMILES CCC(C)[C@H](N)C(=O)N1C[C@H]2C[C@H]2C1C#N
Show InChI InChI=1S/C12H19N3O/c1-3-7(2)11(14)12(16)15-6-8-4-9(8)10(15)5-13/h7-11H,3-4,6,14H2,1-2H3/t7?,8-,9-,10?,11+/m1/s1
PDB
MMDB

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PC cid
PC sid
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Article
PubMed
15n/an/an/an/an/an/an/an/a



Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
In vitro inhibition of porcine Dipeptidylpeptidase IV.


J Med Chem 47: 2587-98 (2004)


Article DOI: 10.1021/jm049924d
BindingDB Entry DOI: 10.7270/Q2FT8MSQ
More data for this
Ligand-Target Pair