BDBM50146045 9-Hydroxy-1,2-dihydro-benzo[f]chromen-3-one::CHEMBL314070

SMILES: Oc1ccc2ccc3OC(=O)CCc3c2c1

InChI Key: InChIKey=PADLXPXZRXQXBU-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50146045   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
NAD-dependent histone deacetylase SIR2 (Saccharomyces cerevisiae)	BDBM50146045 (9-Hydroxy-1,2-dihydro-benzo[f]chromen-3-one | CHEM...) Show SMILES Oc1ccc2ccc3OC(=O)CCc3c2c1 Show InChI InChI=1S/C13H10O3/c14-9-3-1-8-2-5-12-10(11(8)7-9)4-6-13(15)16-12/h1-3,5,7,14H,4,6H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.34E+5	n/a	n/a	n/a	n/a	n/a	n/a
Fred Hutchinson Cancer Research Center Curated by ChEMBL					Assay Description In vitro inhibition of sirtuin 2 was evaluated using yeast whole cell lysates				J Med Chem 47: 2635-44 (2004) Article DOI: 10.1021/jm030473r BindingDB Entry DOI: 10.7270/Q228071B
					More data for this Ligand-Target Pair