BDBM50146065 3-(2-Hydroxy-naphthalen-1-yl)-propionamide::CHEMBL89611

SMILES: NC(=O)CCc1c(O)ccc2ccccc12

InChI Key: InChIKey=ARFRNBQNIMKECT-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50146065   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
NAD-dependent histone deacetylase SIR2 (Saccharomyces cerevisiae)	BDBM50146065 (3-(2-Hydroxy-naphthalen-1-yl)-propionamide | CHEMB...) Show SMILES NC(=O)CCc1c(O)ccc2ccccc12 Show InChI InChI=1S/C13H13NO2/c14-13(16)8-6-11-10-4-2-1-3-9(10)5-7-12(11)15/h1-5,7,15H,6,8H2,(H2,14,16)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.25E+5	n/a	n/a	n/a	n/a	n/a	n/a
Fred Hutchinson Cancer Research Center Curated by ChEMBL					Assay Description In vitro inhibition of sirtuin 2 was evaluated using yeast whole cell lysates				J Med Chem 47: 2635-44 (2004) Article DOI: 10.1021/jm030473r BindingDB Entry DOI: 10.7270/Q228071B
					More data for this Ligand-Target Pair