BDBM50146068 7-Methoxy-1,2-dihydro-benzo[f]chromen-3-one::CHEMBL88830

SMILES: COc1cccc2c3CCC(=O)Oc3ccc12

InChI Key: InChIKey=TVWJMUQAAQLJHL-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50146068   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
NAD-dependent histone deacetylase SIR2 (Saccharomyces cerevisiae)	BDBM50146068 (7-Methoxy-1,2-dihydro-benzo[f]chromen-3-one | CHEM...) Show SMILES COc1cccc2c3CCC(=O)Oc3ccc12 Show InChI InChI=1S/C14H12O3/c1-16-12-4-2-3-9-10(12)5-7-13-11(9)6-8-14(15)17-13/h2-5,7H,6,8H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
Fred Hutchinson Cancer Research Center Curated by ChEMBL					Assay Description In vitro inhibition of sirtuin 2 was evaluated using yeast whole cell lysates				J Med Chem 47: 2635-44 (2004) Article DOI: 10.1021/jm030473r BindingDB Entry DOI: 10.7270/Q228071B
					More data for this Ligand-Target Pair