BDBM50146069 6-Methoxy-1,2-dihydro-benzo[f]chromen-3-one::CHEMBL90386

SMILES: COc1cc2OC(=O)CCc2c2ccccc12

InChI Key: InChIKey=NAPYBKPEYOLTNK-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50146069   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
NAD-dependent histone deacetylase SIR2 (Saccharomyces cerevisiae)	BDBM50146069 (6-Methoxy-1,2-dihydro-benzo[f]chromen-3-one | CHEM...) Show SMILES COc1cc2OC(=O)CCc2c2ccccc12 Show InChI InChI=1S/C14H12O3/c1-16-12-8-13-11(6-7-14(15)17-13)9-4-2-3-5-10(9)12/h2-5,8H,6-7H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
Fred Hutchinson Cancer Research Center Curated by ChEMBL					Assay Description In vitro inhibition of sirtuin 2 was evaluated using yeast whole cell lysates				J Med Chem 47: 2635-44 (2004) Article DOI: 10.1021/jm030473r BindingDB Entry DOI: 10.7270/Q228071B
					More data for this Ligand-Target Pair