BDBM50146082 CHEMBL3763876
SMILES: OC[C@H]1O[C@@]2(CC(=NO2)c2ccc3cc(O)ccc3c2)[C@H](O)[C@@H](O)[C@@H]1O
InChI Key: InChIKey=NIISQLDYQPIYIM-UYTYNIKBSA-N
Data: 4 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Liver glycogen phosphorylase (Rattus norvegicus) | BDBM50146082 (CHEMBL3763876) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 3.01E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Claude Bernard Lyon 1 Curated by ChEMBL | Assay Description Inhibition of glycogen phosphorylase in Wistar rat hepatocytes assessed as decrease in glucagon stimulated glucose release after 3 hrs by glucose oxi... | Eur J Med Chem 108: 444-54 (2016) BindingDB Entry DOI: 10.7270/Q2QR500M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glycogen Phosphorylase (PYGL) (Homo sapiens (Human)) | BDBM50146082 (CHEMBL3763876) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1.38E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Claude Bernard Lyon 1 Curated by ChEMBL | Assay Description Inhibition of glycogen phosphorylase in human hepatocytes assessed as glucagon stimulated glycogen content after 3 hrs by colorimetric GOD method | Eur J Med Chem 108: 444-54 (2016) BindingDB Entry DOI: 10.7270/Q2QR500M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glycogen Phosphorylase (PYGL) (Homo sapiens (Human)) | BDBM50146082 (CHEMBL3763876) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 2.22E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Claude Bernard Lyon 1 Curated by ChEMBL | Assay Description Inhibition of glycogen phosphorylase in human hepatocytes assessed as decrease in glucagon stimulated glucose release after 3 hrs by glucose oxidase ... | Eur J Med Chem 108: 444-54 (2016) BindingDB Entry DOI: 10.7270/Q2QR500M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glycogen phosphorylase, muscle form (Oryctolagus cuniculus (rabbit)) | BDBM50146082 (CHEMBL3763876) | PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1.54E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Claude Bernard Lyon 1 Curated by ChEMBL | Assay Description Inhibition of rabbit muscle glycogen phosphorylase b | Eur J Med Chem 108: 444-54 (2016) BindingDB Entry DOI: 10.7270/Q2QR500M | |||||||||||
More data for this Ligand-Target Pair |