BDBM50146307 Biphenyl-2-carboxylic acid [4-(9-chloro-3,4,11,11a-tetrahydro-1H,5H-2-thia-4a,10-diaza-dibenzo[a,d]cycloheptene-10-carbonyl)-phenyl]-amide::CHEMBL93195

SMILES: Clc1cccc2CN3CCSCC3CN(C(=O)c3ccc(NC(=O)c4ccccc4-c4ccccc4)cc3)c12

InChI Key: InChIKey=SWFWMZCZWMQLGN-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50146307   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vasopressin V2 receptor (Homo sapiens (Human))	BDBM50146307 (Biphenyl-2-carboxylic acid [4-(9-chloro-3,4,11,11a...) Show SMILES Clc1cccc2CN3CCSCC3CN(C(=O)c3ccc(NC(=O)c4ccccc4-c4ccccc4)cc3)c12 Show InChI InChI=1S/C32H28ClN3O2S/c33-29-12-6-9-24-19-35-17-18-39-21-26(35)20-36(30(24)29)32(38)23-13-15-25(16-14-23)34-31(37)28-11-5-4-10-27(28)22-7-2-1-3-8-22/h1-16,26H,17-21H2,(H,34,37)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Inhibition of [3H]AVP binding to recombinant human vasopressin V2 receptor				Bioorg Med Chem Lett 14: 2747-52 (2004) Article DOI: 10.1016/j.bmcl.2004.03.083 BindingDB Entry DOI: 10.7270/Q2QN679W
					More data for this Ligand-Target Pair