BDBM50146325 (E)-3-[3-(2-Hydroxy-3,5-diisopropyl-phenyl)-benzo[b]thiophen-5-yl]-but-2-enoic acid::CHEMBL93571

SMILES: CC(C)c1cc(C(C)C)c(O)c(c1)-c1csc2ccc(cc12)C(\C)=C\C(O)=O

InChI Key: InChIKey=NMHQVMAYMWJCJH-OVCLIPMQSA-N

Data: 2 KI  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50146325   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Retinoic acid receptor RXR-alpha (Homo sapiens (Human))	BDBM50146325 ((E)-3-[3-(2-Hydroxy-3,5-diisopropyl-phenyl)-benzo[...) Show SMILES CC(C)c1cc(C(C)C)c(O)c(c1)-c1csc2ccc(cc12)C(\C)=C\C(O)=O Show InChI InChI=1S/C24H26O3S/c1-13(2)17-10-18(14(3)4)24(27)20(11-17)21-12-28-22-7-6-16(9-19(21)22)15(5)8-23(25)26/h6-14,27H,1-5H3,(H,25,26)/b15-8+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	131	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Ability to displace [3H]-9-cis-RA from Retinoid X receptor alpha in CV-1 cells				Bioorg Med Chem Lett 14: 2759-63 (2004) Article DOI: 10.1016/j.bmcl.2004.03.073 BindingDB Entry DOI: 10.7270/Q2513XNB
					More data for this Ligand-Target Pair
Retinoid receptor (Homo sapiens (Human))	BDBM50146325 ((E)-3-[3-(2-Hydroxy-3,5-diisopropyl-phenyl)-benzo[...) Show SMILES CC(C)c1cc(C(C)C)c(O)c(c1)-c1csc2ccc(cc12)C(\C)=C\C(O)=O Show InChI InChI=1S/C24H26O3S/c1-13(2)17-10-18(14(3)4)24(27)20(11-17)21-12-28-22-7-6-16(9-19(21)22)15(5)8-23(25)26/h6-14,27H,1-5H3,(H,25,26)/b15-8+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Ability to displace [3H]-ATRA from Retinoic acid receptor gamma in CV-1 cells				Bioorg Med Chem Lett 14: 2759-63 (2004) Article DOI: 10.1016/j.bmcl.2004.03.073 BindingDB Entry DOI: 10.7270/Q2513XNB
					More data for this Ligand-Target Pair
Retinoic acid receptor RXR-alpha (Homo sapiens (Human))	BDBM50146325 ((E)-3-[3-(2-Hydroxy-3,5-diisopropyl-phenyl)-benzo[...) Show SMILES CC(C)c1cc(C(C)C)c(O)c(c1)-c1csc2ccc(cc12)C(\C)=C\C(O)=O Show InChI InChI=1S/C24H26O3S/c1-13(2)17-10-18(14(3)4)24(27)20(11-17)21-12-28-22-7-6-16(9-19(21)22)15(5)8-23(25)26/h6-14,27H,1-5H3,(H,25,26)/b15-8+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	1.44E+3	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Effective concentration required for agonistic activity in CV-1 cells expressing RXR-alpha				Bioorg Med Chem Lett 14: 2759-63 (2004) Article DOI: 10.1016/j.bmcl.2004.03.073 BindingDB Entry DOI: 10.7270/Q2513XNB
					More data for this Ligand-Target Pair