BDBM50146436 8-Ethylsulfanyl-3-methyl-5-oxazol-2-yl-3,4-dihydro-2H-naphthalen-1-one::CHEMBL320395

SMILES: CCSc1ccc(-c2ncco2)c2CC(C)CC(=O)c12

InChI Key: InChIKey=IMNDRTREIHGIIE-UHFFFAOYSA-N

Data: 4 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50146436   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
GABA receptor alpha-5/beta-3/gamma-2 subunit (Homo sapiens (Human))	BDBM50146436 (8-Ethylsulfanyl-3-methyl-5-oxazol-2-yl-3,4-dihydro...) Show SMILES CCSc1ccc(-c2ncco2)c2CC(C)CC(=O)c12 Show InChI InChI=1S/C16H17NO2S/c1-3-20-14-5-4-11(16-17-6-7-19-16)12-8-10(2)9-13(18)15(12)14/h4-7,10H,3,8-9H2,1-2H3	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	2.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Curated by ChEMBL					Assay Description Inhibition of [3H]-Ro- 15-1788 binding to human GABA-A receptor alpha-5-beta-3-gamma-2 subunits				Bioorg Med Chem Lett 14: 2871-5 (2004) Article DOI: 10.1016/j.bmcl.2004.03.054 BindingDB Entry DOI: 10.7270/Q2KW5GK5
					More data for this Ligand-Target Pair
GABA receptor alpha-3/beta-3/gamma-2 subunit (Homo sapiens (Human))	BDBM50146436 (8-Ethylsulfanyl-3-methyl-5-oxazol-2-yl-3,4-dihydro...) Show SMILES CCSc1ccc(-c2ncco2)c2CC(C)CC(=O)c12 Show InChI InChI=1S/C16H17NO2S/c1-3-20-14-5-4-11(16-17-6-7-19-16)12-8-10(2)9-13(18)15(12)14/h4-7,10H,3,8-9H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	16	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Curated by ChEMBL					Assay Description Inhibition of [3H]-Ro- 15-1788 binding to recombinant human gamma-aminobutyric-acid A receptor alpha-3-beta-3-gamma-2				Bioorg Med Chem Lett 14: 2871-5 (2004) Article DOI: 10.1016/j.bmcl.2004.03.054 BindingDB Entry DOI: 10.7270/Q2KW5GK5
					More data for this Ligand-Target Pair
GABA receptor alpha-1/beta-3/gamma-2 subunit (Homo sapiens (Human))	BDBM50146436 (8-Ethylsulfanyl-3-methyl-5-oxazol-2-yl-3,4-dihydro...) Show SMILES CCSc1ccc(-c2ncco2)c2CC(C)CC(=O)c12 Show InChI InChI=1S/C16H17NO2S/c1-3-20-14-5-4-11(16-17-6-7-19-16)12-8-10(2)9-13(18)15(12)14/h4-7,10H,3,8-9H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	37	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Curated by ChEMBL					Assay Description Inhibition of [3H]-Ro- 15-1788 binding to recombinant human gamma-aminobutyric-acid A receptor alpha-1-beta-3-gamma-2				Bioorg Med Chem Lett 14: 2871-5 (2004) Article DOI: 10.1016/j.bmcl.2004.03.054 BindingDB Entry DOI: 10.7270/Q2KW5GK5
					More data for this Ligand-Target Pair
GABA receptor alpha-2/beta-3/gamma-2 subunit (Homo sapiens (Human))	BDBM50146436 (8-Ethylsulfanyl-3-methyl-5-oxazol-2-yl-3,4-dihydro...) Show SMILES CCSc1ccc(-c2ncco2)c2CC(C)CC(=O)c12 Show InChI InChI=1S/C16H17NO2S/c1-3-20-14-5-4-11(16-17-6-7-19-16)12-8-10(2)9-13(18)15(12)14/h4-7,10H,3,8-9H2,1-2H3	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	38	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Curated by ChEMBL					Assay Description Inhibition of [3H]-Ro- 15-1788 binding to recombinant human gamma-aminobutyric-acid A receptor alpha-2-beta-3-gamma-2				Bioorg Med Chem Lett 14: 2871-5 (2004) Article DOI: 10.1016/j.bmcl.2004.03.054 BindingDB Entry DOI: 10.7270/Q2KW5GK5
					More data for this Ligand-Target Pair