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BDBM50146458 CHEMBL3764137

SMILES: Cl.NOCc1cc(Br)cc(Br)c1

InChI Key: InChIKey=JXQAASOOGVHBOV-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50146458   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Indoleamine 2,3-dioxygenase 1


(Homo sapiens (Human))
BDBM50146458
PNG
(CHEMBL3764137)
Show SMILES Cl.NOCc1cc(Br)cc(Br)c1
Show InChI InChI=1S/C7H7Br2NO.ClH/c8-6-1-5(4-11-10)2-7(9)3-6;/h1-3H,4,10H2;1H
PDB
MMDB

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PubMed
n/an/a 4.20E+3n/an/an/an/an/an/a



Bryn Mawr College

Curated by ChEMBL


Assay Description
Inhibition of recombinant human IDO1 assessed as reduction in kynurenine production using L-tryptophan as substrate after 60 mins by microplate reade...


Eur J Med Chem 108: 564-76 (2016)


BindingDB Entry DOI: 10.7270/Q26Q203T
More data for this
Ligand-Target Pair