BDBM50146460 CHEMBL3763688
SMILES: Cl.NOCc1ccc(I)cc1
InChI Key: InChIKey=QKTGWFUBZHRJRK-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Indoleamine 2,3-dioxygenase 1 (Homo sapiens (Human)) | BDBM50146460 (CHEMBL3763688) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 164 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bryn Mawr College Curated by ChEMBL | Assay Description Inhibition of recombinant human IDO1 assessed as reduction in kynurenine production using L-tryptophan as substrate after 60 mins by Michaelis-Menton... | Eur J Med Chem 108: 564-76 (2016) BindingDB Entry DOI: 10.7270/Q26Q203T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 3A4 (Homo sapiens (Human)) | BDBM50146460 (CHEMBL3763688) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 7.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Bryn Mawr College Curated by ChEMBL | Assay Description Inhibition of CYP3A4 (unknown origin) | Eur J Med Chem 108: 564-76 (2016) BindingDB Entry DOI: 10.7270/Q26Q203T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Indoleamine 2,3-dioxygenase 1 (Homo sapiens (Human)) | BDBM50146460 (CHEMBL3763688) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 82 | n/a | n/a | n/a | n/a | n/a | n/a |
Bryn Mawr College Curated by ChEMBL | Assay Description Inhibition of IFN gamma induced human IDO1 in HeLa cells assessed as reduction in kynurenine production treated with 5-fold serial dilution beginning... | Eur J Med Chem 108: 564-76 (2016) BindingDB Entry DOI: 10.7270/Q26Q203T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Indoleamine 2,3-dioxygenase 1 (Homo sapiens (Human)) | BDBM50146460 (CHEMBL3763688) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 210 | n/a | n/a | n/a | n/a | n/a | n/a |
Bryn Mawr College Curated by ChEMBL | Assay Description Inhibition of recombinant human IDO1 assessed as reduction in kynurenine production using L-tryptophan as substrate after 60 mins by microplate reade... | Eur J Med Chem 108: 564-76 (2016) BindingDB Entry DOI: 10.7270/Q26Q203T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Indoleamine 2,3-dioxygenase 1 (Homo sapiens (Human)) | BDBM50146460 (CHEMBL3763688) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 95 | n/a | n/a | n/a | n/a | n/a | n/a |
Bryn Mawr College Curated by ChEMBL | Assay Description Inhibition of IFN gamma induced human IDO1 in HeLa cells assessed as reduction in kynurenine production treated with 3-fold serial dilution beginning... | Eur J Med Chem 108: 564-76 (2016) BindingDB Entry DOI: 10.7270/Q26Q203T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Catalase (Homo sapiens (Human)) | BDBM50146460 (CHEMBL3763688) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Bryn Mawr College Curated by ChEMBL | Assay Description Inhibition of catalase (unknown origin) using hydrogen peroxide as substrate | Eur J Med Chem 108: 564-76 (2016) BindingDB Entry DOI: 10.7270/Q26Q203T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Indoleamine 2,3-dioxygenase 1 (Homo sapiens (Human)) | BDBM50146460 (CHEMBL3763688) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 180 | n/a | n/a | n/a | n/a | n/a | n/a |
Bryn Mawr College Curated by ChEMBL | Assay Description Inhibition of doxycycline-induced human IDO1 expressed in Trex cells assessed as reduction in kynurenine production treated with 5-fold serial diluti... | Eur J Med Chem 108: 564-76 (2016) BindingDB Entry DOI: 10.7270/Q26Q203T | |||||||||||
More data for this Ligand-Target Pair |