BDBM50146468 CHEMBL98852::N-Hydroxy-N-[2-[4-(2-methyl-quinolin-4-ylmethoxy)-benzenesulfonyl]-1-(4-oxo-cyclohexylidenemethyl)-ethyl]-formamide

SMILES: [#6]-c1cc(-[#6]-[#8]-c2ccc(cc2)S(=O)(=O)[#6]-[#6](\[#6]=[#6]-2/[#6]-[#6]-[#6](=O)-[#6]-[#6]-2)-[#7](-[#8])-[#6]=O)c2ccccc2n1

InChI Key: InChIKey=VDOSRWCTGZRCFD-UHFFFAOYSA-N

Data: 6 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50146468   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Matrix metalloproteinase 17 (Homo sapiens (Human))	BDBM50146468 (CHEMBL98852 | N-Hydroxy-N-[2-[4-(2-methyl-quinolin...) Show SMILES [#6]-c1cc(-[#6]-[#8]-c2ccc(cc2)S(=O)(=O)[#6]-[#6](\[#6]=[#6]-2/[#6]-[#6]-[#6](=O)-[#6]-[#6]-2)-[#7](-[#8])-[#6]=O)c2ccccc2n1 Show InChI InChI=1S/C27H28N2O6S/c1-19-14-21(26-4-2-3-5-27(26)28-19)16-35-24-10-12-25(13-11-24)36(33,34)17-22(29(32)18-30)15-20-6-8-23(31)9-7-20/h2-5,10-15,18,22,32H,6-9,16-17H2,1H3	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Kaken Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Inhibition of matrix metalloproteinase-17				Bioorg Med Chem Lett 14: 2897-900 (2004) Article DOI: 10.1016/j.bmcl.2004.03.048 BindingDB Entry DOI: 10.7270/Q27S7N7C
					More data for this Ligand-Target Pair
Matrix metalloproteinase-9 (Homo sapiens (Human))	BDBM50146468 (CHEMBL98852 | N-Hydroxy-N-[2-[4-(2-methyl-quinolin...) Show SMILES [#6]-c1cc(-[#6]-[#8]-c2ccc(cc2)S(=O)(=O)[#6]-[#6](\[#6]=[#6]-2/[#6]-[#6]-[#6](=O)-[#6]-[#6]-2)-[#7](-[#8])-[#6]=O)c2ccccc2n1 Show InChI InChI=1S/C27H28N2O6S/c1-19-14-21(26-4-2-3-5-27(26)28-19)16-35-24-10-12-25(13-11-24)36(33,34)17-22(29(32)18-30)15-20-6-8-23(31)9-7-20/h2-5,10-15,18,22,32H,6-9,16-17H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Kaken Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Inhibition of matrix metalloproteinase-9				Bioorg Med Chem Lett 14: 2897-900 (2004) Article DOI: 10.1016/j.bmcl.2004.03.048 BindingDB Entry DOI: 10.7270/Q27S7N7C
					More data for this Ligand-Target Pair
Collagenase 3 (Homo sapiens (Human))	BDBM50146468 (CHEMBL98852 | N-Hydroxy-N-[2-[4-(2-methyl-quinolin...) Show SMILES [#6]-c1cc(-[#6]-[#8]-c2ccc(cc2)S(=O)(=O)[#6]-[#6](\[#6]=[#6]-2/[#6]-[#6]-[#6](=O)-[#6]-[#6]-2)-[#7](-[#8])-[#6]=O)c2ccccc2n1 Show InChI InChI=1S/C27H28N2O6S/c1-19-14-21(26-4-2-3-5-27(26)28-19)16-35-24-10-12-25(13-11-24)36(33,34)17-22(29(32)18-30)15-20-6-8-23(31)9-7-20/h2-5,10-15,18,22,32H,6-9,16-17H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Kaken Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Inhibition of matrix metalloproteinase-13				Bioorg Med Chem Lett 14: 2897-900 (2004) Article DOI: 10.1016/j.bmcl.2004.03.048 BindingDB Entry DOI: 10.7270/Q27S7N7C
					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50146468 (CHEMBL98852 | N-Hydroxy-N-[2-[4-(2-methyl-quinolin...) Show SMILES [#6]-c1cc(-[#6]-[#8]-c2ccc(cc2)S(=O)(=O)[#6]-[#6](\[#6]=[#6]-2/[#6]-[#6]-[#6](=O)-[#6]-[#6]-2)-[#7](-[#8])-[#6]=O)c2ccccc2n1 Show InChI InChI=1S/C27H28N2O6S/c1-19-14-21(26-4-2-3-5-27(26)28-19)16-35-24-10-12-25(13-11-24)36(33,34)17-22(29(32)18-30)15-20-6-8-23(31)9-7-20/h2-5,10-15,18,22,32H,6-9,16-17H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
Kaken Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Inhibition of matrix metalloproteinase-2				Bioorg Med Chem Lett 14: 2897-900 (2004) Article DOI: 10.1016/j.bmcl.2004.03.048 BindingDB Entry DOI: 10.7270/Q27S7N7C
					More data for this Ligand-Target Pair
Disintegrin and metalloproteinase domain-containing protein 17 (Homo sapiens (Human))	BDBM50146468 (CHEMBL98852 | N-Hydroxy-N-[2-[4-(2-methyl-quinolin...) Show SMILES [#6]-c1cc(-[#6]-[#8]-c2ccc(cc2)S(=O)(=O)[#6]-[#6](\[#6]=[#6]-2/[#6]-[#6]-[#6](=O)-[#6]-[#6]-2)-[#7](-[#8])-[#6]=O)c2ccccc2n1 Show InChI InChI=1S/C27H28N2O6S/c1-19-14-21(26-4-2-3-5-27(26)28-19)16-35-24-10-12-25(13-11-24)36(33,34)17-22(29(32)18-30)15-20-6-8-23(31)9-7-20/h2-5,10-15,18,22,32H,6-9,16-17H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.5	n/a	n/a	n/a	n/a	n/a	n/a
Kaken Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Inhibition of Tumor necrosis factor alpha converting enzyme				Bioorg Med Chem Lett 14: 2897-900 (2004) Article DOI: 10.1016/j.bmcl.2004.03.048 BindingDB Entry DOI: 10.7270/Q27S7N7C
					More data for this Ligand-Target Pair
Stromelysin-1 (Homo sapiens (Human))	BDBM50146468 (CHEMBL98852 | N-Hydroxy-N-[2-[4-(2-methyl-quinolin...) Show SMILES [#6]-c1cc(-[#6]-[#8]-c2ccc(cc2)S(=O)(=O)[#6]-[#6](\[#6]=[#6]-2/[#6]-[#6]-[#6](=O)-[#6]-[#6]-2)-[#7](-[#8])-[#6]=O)c2ccccc2n1 Show InChI InChI=1S/C27H28N2O6S/c1-19-14-21(26-4-2-3-5-27(26)28-19)16-35-24-10-12-25(13-11-24)36(33,34)17-22(29(32)18-30)15-20-6-8-23(31)9-7-20/h2-5,10-15,18,22,32H,6-9,16-17H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	6.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Kaken Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Inhibition of matrix metalloproteinase-3				Bioorg Med Chem Lett 14: 2897-900 (2004) Article DOI: 10.1016/j.bmcl.2004.03.048 BindingDB Entry DOI: 10.7270/Q27S7N7C
					More data for this Ligand-Target Pair