BDBM50146905 4-{(E)-2-[({[2,4-Dichloro-3-(4-methoxy-2-methyl-quinolin-8-yloxymethyl)-phenyl]-methyl-carbamoyl}-methyl)-carbamoyl]-vinyl}-N-methyl-benzamide; hydrochloride::CHEMBL538022

SMILES: CNC(=O)c1ccc(\C=C\C(=O)NCC(=O)N(C)c2ccc(Cl)c(COc3cccc4c(OC)cc(C)nc34)c2Cl)cc1

InChI Key: InChIKey=VOOAWTUCIAYTJR-XNTDXEJSSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50146905   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
BDKRB2 (Homo sapiens (Human))	BDBM50146905 (4-{(E)-2-[({[2,4-Dichloro-3-(4-methoxy-2-methyl-qu...) Show SMILES CNC(=O)c1ccc(\C=C\C(=O)NCC(=O)N(C)c2ccc(Cl)c(COc3cccc4c(OC)cc(C)nc34)c2Cl)cc1 Show InChI InChI=1S/C32H30Cl2N4O5/c1-19-16-27(42-4)22-6-5-7-26(31(22)37-19)43-18-23-24(33)13-14-25(30(23)34)38(3)29(40)17-36-28(39)15-10-20-8-11-21(12-9-20)32(41)35-2/h5-16H,17-18H2,1-4H3,(H,35,41)(H,36,39)/b15-10+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.10	n/a	n/a	n/a	n/a	n/a	n/a
Fujisawa Pharmaceutical Co. Ltd. Curated by ChEMBL					Assay Description Inhibition of [3H]BK (1.0 nM) binding to the human bradykinin receptor B2, expressed in CHO cells				J Med Chem 47: 2853-63 (2004) Article DOI: 10.1021/jm030468n BindingDB Entry DOI: 10.7270/Q2JM2BCM
					More data for this Ligand-Target Pair
BDKRB2 (Homo sapiens (Human))	BDBM50146905 (4-{(E)-2-[({[2,4-Dichloro-3-(4-methoxy-2-methyl-qu...) Show SMILES CNC(=O)c1ccc(\C=C\C(=O)NCC(=O)N(C)c2ccc(Cl)c(COc3cccc4c(OC)cc(C)nc34)c2Cl)cc1 Show InChI InChI=1S/C32H30Cl2N4O5/c1-19-16-27(42-4)22-6-5-7-26(31(22)37-19)43-18-23-24(33)13-14-25(30(23)34)38(3)29(40)17-36-28(39)15-10-20-8-11-21(12-9-20)32(41)35-2/h5-16H,17-18H2,1-4H3,(H,35,41)(H,36,39)/b15-10+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.230	n/a	n/a	n/a	n/a	n/a	n/a
Fujisawa Pharmaceutical Co. Ltd. Curated by ChEMBL					Assay Description Concentration required to inhibit specific binding of [3H]-BK(0.06 nM) to the bradykinin receptor B2				J Med Chem 47: 2853-63 (2004) Article DOI: 10.1021/jm030468n BindingDB Entry DOI: 10.7270/Q2JM2BCM
					More data for this Ligand-Target Pair