BDBM50147021 3-[3-(2,6-Diisopropyl-phenyl)-ureido]-2,3,4,9-tetrahydro-1H-carbazole-3-carboxylic acid (1-pyridin-2-yl-cyclohexylmethyl)-amide::CHEMBL318548

SMILES: CC(C)c1cccc(C(C)C)c1NC(=O)NC1(CCc2[nH]c3ccccc3c2C1)C(=O)NCC1(CCCCC1)c1ccccn1

InChI Key: InChIKey=XCCNMGMMSHQXLV-UHFFFAOYSA-N

Data: 1 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50147021   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuromedin B receptor (Homo sapiens (Human))	BDBM50147021 (3-[3-(2,6-Diisopropyl-phenyl)-ureido]-2,3,4,9-tetr...) Show SMILES CC(C)c1cccc(C(C)C)c1NC(=O)NC1(CCc2[nH]c3ccccc3c2C1)C(=O)NCC1(CCCCC1)c1ccccn1 Show InChI InChI=1S/C38H47N5O2/c1-25(2)27-14-12-15-28(26(3)4)34(27)42-36(45)43-38(21-18-32-30(23-38)29-13-6-7-16-31(29)41-32)35(44)40-24-37(19-9-5-10-20-37)33-17-8-11-22-39-33/h6-8,11-17,22,25-26,41H,5,9-10,18-21,23-24H2,1-4H3,(H,40,44)(H2,42,43,45)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	320	n/a	n/a	n/a	n/a	n/a	n/a
Tularik Inc. Curated by ChEMBL					Assay Description Affinity of [125I]-[D-Tyr0]-NMB to human Neuromedin B receptor expressed in HEK293 cells				Bioorg Med Chem Lett 14: 3037-42 (2004) Article DOI: 10.1016/j.bmcl.2004.04.045 BindingDB Entry DOI: 10.7270/Q2PR7VF7
					More data for this Ligand-Target Pair
NMBR (Homo sapiens (Human))	BDBM50147021 (3-[3-(2,6-Diisopropyl-phenyl)-ureido]-2,3,4,9-tetr...) Show SMILES CC(C)c1cccc(C(C)C)c1NC(=O)NC1(CCc2[nH]c3ccccc3c2C1)C(=O)NCC1(CCCCC1)c1ccccn1 Show InChI InChI=1S/C38H47N5O2/c1-25(2)27-14-12-15-28(26(3)4)34(27)42-36(45)43-38(21-18-32-30(23-38)29-13-6-7-16-31(29)41-32)35(44)40-24-37(19-9-5-10-20-37)33-17-8-11-22-39-33/h6-8,11-17,22,25-26,41H,5,9-10,18-21,23-24H2,1-4H3,(H,40,44)(H2,42,43,45)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	603	n/a	n/a	n/a	n/a
Tularik Inc. Curated by ChEMBL					Assay Description Agonistic activity was determined against human Neuromedin B receptor transfected in HEK293 cells as accumulation levels of inositol phosphate				Bioorg Med Chem Lett 14: 3037-42 (2004) Article DOI: 10.1016/j.bmcl.2004.04.045 BindingDB Entry DOI: 10.7270/Q2PR7VF7
					More data for this Ligand-Target Pair