BDBM50147023 3-[3-(2,6-Diisopropyl-phenyl)-ureido]-4,7-difluoro-2,3,4,9-tetrahydro-1H-carbazole-3-carboxylic acid (1-pyridin-2-yl-cyclohexylmethyl)-amide::CHEMBL421216

SMILES: CC(C)c1cccc(C(C)C)c1NC(=O)NC1(CCc2[nH]c3cc(F)ccc3c2C1F)C(=O)NCC1(CCCCC1)c1ccccn1

InChI Key: InChIKey=WQEIMXLYYCJJQH-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50147023   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
NMBR (Homo sapiens (Human))	BDBM50147023 (3-[3-(2,6-Diisopropyl-phenyl)-ureido]-4,7-difluoro...) Show SMILES CC(C)c1cccc(C(C)C)c1NC(=O)NC1(CCc2[nH]c3cc(F)ccc3c2C1F)C(=O)NCC1(CCCCC1)c1ccccn1 Show InChI InChI=1S/C38H45F2N5O2/c1-23(2)26-11-10-12-27(24(3)4)33(26)44-36(47)45-38(19-16-29-32(34(38)40)28-15-14-25(39)21-30(28)43-29)35(46)42-22-37(17-7-5-8-18-37)31-13-6-9-20-41-31/h6,9-15,20-21,23-24,34,43H,5,7-8,16-19,22H2,1-4H3,(H,42,46)(H2,44,45,47)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.01E+3	n/a	n/a	n/a	n/a	n/a	n/a
Tularik Inc. Curated by ChEMBL					Assay Description Affinity of [125I]-[D-Tyr0]-NMB to human Neuromedin B receptor expressed in HEK293 cells				Bioorg Med Chem Lett 14: 3037-42 (2004) Article DOI: 10.1016/j.bmcl.2004.04.045 BindingDB Entry DOI: 10.7270/Q2PR7VF7
					More data for this Ligand-Target Pair