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BDBM50147040 3-[3-(2,6-Diisopropyl-phenyl)-ureido]-5-trifluoromethoxy-2,3,4,9-tetrahydro-1H-carbazole-3-carboxylic acid (1-pyridin-2-yl-cyclohexylmethyl)-amide::CHEMBL328166

SMILES: CC(C)c1cccc(C(C)C)c1NC(=O)NC1(CCc2[nH]c3cccc(OC(F)(F)F)c3c2C1)C(=O)NCC1(CCCCC1)c1ccccn1

InChI Key: InChIKey=XFUKUPKKDDBKAJ-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50147040   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
NMBR


(Homo sapiens (Human))		BDBM50147040
PNG
(3-[3-(2,6-Diisopropyl-phenyl)-ureido]-5-trifluorom...)
Show SMILES CC(C)c1cccc(C(C)C)c1NC(=O)NC1(CCc2[nH]c3cccc(OC(F)(F)F)c3c2C1)C(=O)NCC1(CCCCC1)c1ccccn1
Show InChI InChI=1S/C39H46F3N5O3/c1-24(2)26-12-10-13-27(25(3)4)34(26)46-36(49)47-38(35(48)44-23-37(18-7-5-8-19-37)32-16-6-9-21-43-32)20-17-29-28(22-38)33-30(45-29)14-11-15-31(33)50-39(40,41)42/h6,9-16,21,24-25,45H,5,7-8,17-20,22-23H2,1-4H3,(H,44,48)(H2,46,47,49)
KEGG

UniProtKB/SwissProt

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PC sid
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Article
PubMed
n/an/a 1.89E+3n/an/an/an/an/an/a



Tularik Inc.

Curated by ChEMBL


Assay Description
Affinity of [125I]-[D-Tyr0]-NMB to human Neuromedin B receptor expressed in HEK293 cells

Bioorg Med Chem Lett 14: 3037-42 (2004)


Article DOI: 10.1016/j.bmcl.2004.04.045
BindingDB Entry DOI: 10.7270/Q2PR7VF7
More data for this
Ligand-Target Pair