BDBM50147049 5-Ethylsulfanyl-4-(4-phenyl-thiazol-2-yl)-thiophene-2-carboxamidine::CHEMBL105102

SMILES: CCSc1sc(cc1-c1nc(cs1)-c1ccccc1)C(N)=N

InChI Key: InChIKey=LCFWLZQDVKEWFJ-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50147049   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Complement C1s (Homo sapiens (Human))	BDBM50147049 (5-Ethylsulfanyl-4-(4-phenyl-thiazol-2-yl)-thiophen...) Show SMILES CCSc1sc(cc1-c1nc(cs1)-c1ccccc1)C(N)=N Show InChI InChI=1S/C16H15N3S3/c1-2-20-16-11(8-13(22-16)14(17)18)15-19-12(9-21-15)10-6-4-3-5-7-10/h3-9H,2H2,1H3,(H3,17,18)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
3-Dimensional Pharmaceuticals Inc Curated by ChEMBL					Assay Description In vitro binding affinity towards human Complement C1s subcomponent				Bioorg Med Chem Lett 14: 3043-7 (2004) Article DOI: 10.1016/j.bmcl.2004.04.034 BindingDB Entry DOI: 10.7270/Q2K35T33
					More data for this Ligand-Target Pair