BDBM50147052 5-Benzylsulfanyl-4-(4-phenyl-thiazol-2-yl)-thiophene-2-carboxamidine::CHEMBL104368

SMILES: NC(=N)c1cc(c(SCc2ccccc2)s1)-c1nc(cs1)-c1ccccc1

InChI Key: InChIKey=XMNPQLITWKAPGY-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50147052   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Complement C1s (Homo sapiens (Human))	BDBM50147052 (5-Benzylsulfanyl-4-(4-phenyl-thiazol-2-yl)-thiophe...) Show SMILES NC(=N)c1cc(c(SCc2ccccc2)s1)-c1nc(cs1)-c1ccccc1 Show InChI InChI=1S/C21H17N3S3/c22-19(23)18-11-16(21(27-18)26-12-14-7-3-1-4-8-14)20-24-17(13-25-20)15-9-5-2-6-10-15/h1-11,13H,12H2,(H3,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
3-Dimensional Pharmaceuticals Inc Curated by ChEMBL					Assay Description In vitro binding affinity towards human Complement C1s subcomponent				Bioorg Med Chem Lett 14: 3043-7 (2004) Article DOI: 10.1016/j.bmcl.2004.04.034 BindingDB Entry DOI: 10.7270/Q2K35T33
					More data for this Ligand-Target Pair