BDBM50147053 5-Methylsulfanyl-4-(5-phenyl-thiazol-2-yl)-thiophene-2-carboxamidine::CHEMBL322672

SMILES: CSc1sc(cc1-c1ncc(s1)-c1ccccc1)C(N)=N

InChI Key: InChIKey=BBOOVCSXOALWHH-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50147053   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Complement C1s (Homo sapiens (Human))	BDBM50147053 (5-Methylsulfanyl-4-(5-phenyl-thiazol-2-yl)-thiophe...) Show SMILES CSc1sc(cc1-c1ncc(s1)-c1ccccc1)C(N)=N Show InChI InChI=1S/C15H13N3S3/c1-19-15-10(7-11(21-15)13(16)17)14-18-8-12(20-14)9-5-3-2-4-6-9/h2-8H,1H3,(H3,16,17)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.25E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
3-Dimensional Pharmaceuticals Inc Curated by ChEMBL					Assay Description In vitro binding affinity towards human Complement C1s subcomponent				Bioorg Med Chem Lett 14: 3043-7 (2004) Article DOI: 10.1016/j.bmcl.2004.04.034 BindingDB Entry DOI: 10.7270/Q2K35T33
					More data for this Ligand-Target Pair