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BDBM50147099 8-(furan-2-yl)-7-methoxy-2-naphthimidamide::8-Furan-2-yl-7-methoxy-naphthalene-2-carboxamidine::CHEMBL418805

SMILES: COc1ccc2ccc(cc2c1-c1ccco1)C(N)=N

InChI Key: InChIKey=FGXHCLGVMUGKNO-UHFFFAOYSA-N

Data: 2 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50147099   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Urokinase-type plasminogen activator


(Homo sapiens (Human))
BDBM50147099
PNG
(8-(furan-2-yl)-7-methoxy-2-naphthimidamide | 8-Fur...)
Show SMILES COc1ccc2ccc(cc2c1-c1ccco1)C(N)=N
Show InChI InChI=1S/C16H14N2O2/c1-19-13-7-6-10-4-5-11(16(17)18)9-12(10)15(13)14-3-2-8-20-14/h2-9H,1H3,(H3,17,18)
PDB
MMDB

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PC cid
PC sid
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Article
PubMed
2.00E+3n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of urokinase


J Med Chem 52: 3159-65 (2009)


Article DOI: 10.1021/jm801444x
BindingDB Entry DOI: 10.7270/Q2FF3TM8
More data for this
Ligand-Target Pair
Urokinase-type plasminogen activator


(Homo sapiens (Human))
BDBM50147099
PNG
(8-(furan-2-yl)-7-methoxy-2-naphthimidamide | 8-Fur...)
Show SMILES COc1ccc2ccc(cc2c1-c1ccco1)C(N)=N
Show InChI InChI=1S/C16H14N2O2/c1-19-13-7-6-10-4-5-11(16(17)18)9-12(10)15(13)14-3-2-8-20-14/h2-9H,1H3,(H3,17,18)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Article
PubMed
2.10E+3n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity towards Urokinase-type plasminogen activator (urokinase)


Bioorg Med Chem Lett 14: 3063-8 (2004)


Article DOI: 10.1016/j.bmcl.2004.04.030
BindingDB Entry DOI: 10.7270/Q29K49PG
More data for this
Ligand-Target Pair