BDBM50147120 2-Methylamino-ethanol::2-hydroxy-N-methylethanaminium::CHEMBL104083
SMILES: CNCCO
InChI Key: InChIKey=OPKOKAMJFNKNAS-UHFFFAOYSA-N
Data: 2 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Creatine transporter (Rattus norvegicus) | BDBM50147120 (2-Methylamino-ethanol | 2-hydroxy-N-methylethanami...) | Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | 1.27E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Texas Tech University Health Sciences Center Curated by ChEMBL | Assay Description Inhibition of [3H]-choline brain uptake was determined by in situ brain perfusion studies in male rats | Bioorg Med Chem Lett 14: 3085-92 (2004) Article DOI: 10.1016/j.bmcl.2004.04.020 BindingDB Entry DOI: 10.7270/Q2BG2PJR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Choline transporter (Mus musculus) | BDBM50147120 (2-Methylamino-ethanol | 2-hydroxy-N-methylethanami...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | 3.80E+6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Northeastern Ohio Universities Colleges of Medicine and Pharmacy Curated by ChEMBL | Assay Description Inhibition of [3H]choline uptake at choline transporter 1 in mouse brain synaptosome | Bioorg Med Chem Lett 20: 4870-7 (2010) Article DOI: 10.1016/j.bmcl.2010.06.090 BindingDB Entry DOI: 10.7270/Q29C6XMQ | |||||||||||
More data for this Ligand-Target Pair |