BDBM50147171 CHEMBL3764657
SMILES: COc1ccc2NC(=O)\C(=N/c3ccc(cc3)C(=O)Nc3ccc(cc3)S(N)(=O)=O)c2c1
InChI Key: InChIKey=IVZDIJOFMITBFF-UHFFFAOYSA-N
Data: 4 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Carbonic anhydrase 12 (Homo sapiens (Human)) | BDBM50147171 (CHEMBL3764657) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | 0.470 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Egyptian Russian University Curated by ChEMBL | Assay Description Inhibition of recombinant human carbonic anhydrase 12 incubated for 15 mins prior to testing by stopped flow carbon dioxide hydrase assay | Eur J Med Chem 110: 259-66 (2016) BindingDB Entry DOI: 10.7270/Q2D79D8Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 2 (Homo sapiens (Human)) | BDBM50147171 (CHEMBL3764657) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | 15 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Egyptian Russian University Curated by ChEMBL | Assay Description Inhibition of recombinant human carbonic anhydrase 2 incubated for 15 mins prior to testing by stopped flow carbon dioxide hydrase assay | Eur J Med Chem 110: 259-66 (2016) BindingDB Entry DOI: 10.7270/Q2D79D8Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 1 (Homo sapiens (Human)) | BDBM50147171 (CHEMBL3764657) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | 29 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Egyptian Russian University Curated by ChEMBL | Assay Description Inhibition of recombinant human carbonic anhydrase 1 incubated for 15 mins prior to testing by stopped flow carbon dioxide hydrase assay | Eur J Med Chem 110: 259-66 (2016) BindingDB Entry DOI: 10.7270/Q2D79D8Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 9 (Homo sapiens (Human)) | BDBM50147171 (CHEMBL3764657) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | 175 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Egyptian Russian University Curated by ChEMBL | Assay Description Inhibition of recombinant human carbonic anhydrase 9 incubated for 15 mins prior to testing by stopped flow carbon dioxide hydrase assay | Eur J Med Chem 110: 259-66 (2016) BindingDB Entry DOI: 10.7270/Q2D79D8Q | |||||||||||
More data for this Ligand-Target Pair |