BDBM50147399 2'-(2-Hydroxy-phenyl)-[2,4']bibenzooxazolyl-4-carboxylic acid methyl ester::CHEMBL111574::methyl 2-(2-(2-hydroxyphenyl)benzo[d]oxazol-4-yl)benzo[d]oxazole-4-carboxylate

SMILES: COC(=O)c1cccc2oc(nc12)-c1cccc2oc(nc12)-c1ccccc1O

InChI Key: InChIKey=NGKIDJMAXLRJRL-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50147399   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Topoisomerase II alpha (HuTopoIIα) (Homo sapiens (Human))	BDBM50147399 (2'-(2-Hydroxy-phenyl)-[2,4']bibenzooxazolyl-4-carb...) Show SMILES COC(=O)c1cccc2oc(nc12)-c1cccc2oc(nc12)-c1ccccc1O Show InChI InChI=1S/C22H14N2O5/c1-27-22(26)14-8-5-11-17-19(14)24-21(29-17)13-7-4-10-16-18(13)23-20(28-16)12-6-2-3-9-15(12)25/h2-11,25H,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Maryland Curated by ChEMBL					Assay Description Inhibitory activity of compound against human DNA topoisomerase II, alpha was evaluated by ability to interfere with the relaxation of supercoiled pl...				Bioorg Med Chem Lett 14: 3221-6 (2004) Article DOI: 10.1016/j.bmcl.2004.03.095 BindingDB Entry DOI: 10.7270/Q24T6HTC
					More data for this Ligand-Target Pair
DNA topoisomerase II (Homo sapiens (Human))	BDBM50147399 (2'-(2-Hydroxy-phenyl)-[2,4']bibenzooxazolyl-4-carb...) Show SMILES COC(=O)c1cccc2oc(nc12)-c1cccc2oc(nc12)-c1ccccc1O Show InChI InChI=1S/C22H14N2O5/c1-27-22(26)14-8-5-11-17-19(14)24-21(29-17)13-7-4-10-16-18(13)23-20(28-16)12-6-2-3-9-15(12)25/h2-11,25H,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Maryland Curated by ChEMBL					Assay Description Inhibitory activity of compound against human DNA topoisomerase II, alpha was evaluated by ability to interfere with the relaxation of supercoiled pl...				Bioorg Med Chem Lett 14: 3221-6 (2004) Article DOI: 10.1016/j.bmcl.2004.03.095 BindingDB Entry DOI: 10.7270/Q24T6HTC
					More data for this Ligand-Target Pair