BDBM50147400 2'-Phenyl-[2,4']bibenzooxazolyl-4-carboxylic acid methyl ester::CHEMBL324426

SMILES: COC(=O)c1cccc2oc(nc12)-c1cccc2oc(nc12)-c1ccccc1

InChI Key: InChIKey=FROOINYHUVLXOX-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50147400   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
DNA topoisomerase 2-alpha (Homo sapiens (Human))	BDBM50147400 (2'-Phenyl-[2,4']bibenzooxazolyl-4-carboxylic acid ...) Show SMILES COC(=O)c1cccc2oc(nc12)-c1cccc2oc(nc12)-c1ccccc1 Show InChI InChI=1S/C22H14N2O4/c1-26-22(25)15-10-6-12-17-19(15)24-21(28-17)14-9-5-11-16-18(14)23-20(27-16)13-7-3-2-4-8-13/h2-12H,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Maryland Curated by ChEMBL					Assay Description Inhibitory concentration against human DNA topoisomerase II, alpha mediated relaxation of pBR322				Bioorg Med Chem Lett 14: 3221-6 (2004) Article DOI: 10.1016/j.bmcl.2004.03.095 BindingDB Entry DOI: 10.7270/Q24T6HTC
					More data for this Ligand-Target Pair