BDBM50147466 3-(1-Ethyl-1H-pyrrolo[2,3-b]pyridin-3-yl)-4-[1-(3-hydroxy-propyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]-pyrrole-2,5-dione::CHEMBL110000

SMILES: CCn1cc(C2=C(C(=O)NC2=O)c2cn(CCCO)c3ncccc23)c2cccnc12

InChI Key: InChIKey=ZBUHFSOGWXBHEF-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50147466   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
PKC alpha and beta-2 (Homo sapiens (Human))	BDBM50147466 (3-(1-Ethyl-1H-pyrrolo[2,3-b]pyridin-3-yl)-4-[1-(3-...) Show SMILES CCn1cc(C2=C(C(=O)NC2=O)c2cn(CCCO)c3ncccc23)c2cccnc12 |t:5| Show InChI InChI=1S/C23H21N5O3/c1-2-27-12-16(14-6-3-8-24-20(14)27)18-19(23(31)26-22(18)30)17-13-28(10-5-11-29)21-15(17)7-4-9-25-21/h3-4,6-9,12-13,29H,2,5,10-11H2,1H3,(H,26,30,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.07E+3	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research & Development Curated by ChEMBL					Assay Description Inhibitory concentration against human protein kinase C-betaII using histone as substrate				Bioorg Med Chem Lett 14: 3245-50 (2004) Article DOI: 10.1016/j.bmcl.2004.03.090 BindingDB Entry DOI: 10.7270/Q2W958NH
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM50147466 (3-(1-Ethyl-1H-pyrrolo[2,3-b]pyridin-3-yl)-4-[1-(3-...) Show SMILES CCn1cc(C2=C(C(=O)NC2=O)c2cn(CCCO)c3ncccc23)c2cccnc12 |t:5| Show InChI InChI=1S/C23H21N5O3/c1-2-27-12-16(14-6-3-8-24-20(14)27)18-19(23(31)26-22(18)30)17-13-28(10-5-11-29)21-15(17)7-4-9-25-21/h3-4,6-9,12-13,29H,2,5,10-11H2,1H3,(H,26,30,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	65	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research & Development Curated by ChEMBL					Assay Description Inhibitory concentration against rabbit glycogen synthase kinase-3 beta using protein phosphatase inhibitor-2 as substrate				Bioorg Med Chem Lett 14: 3245-50 (2004) Article DOI: 10.1016/j.bmcl.2004.03.090 BindingDB Entry DOI: 10.7270/Q2W958NH
					More data for this Ligand-Target Pair